Table 2: Differentially expressed genes involved in apoptosis detected by significant enrichment analysis of GO terms using the R language software package.

GenesGenBank accessionFold changeGene description

PDCD7NM_005707−2.20Programmed cell death 7
RRAGANM_0065702.03Ras-related GTP binding A
DAPK3NM_0013482.04Death-associated protein kinase 3
PUF60NM_014281−2.00Poly-U binding splicing factor 60kda isoform c
FOXO3NM_0014552.16Forkhead box O3A
ARHGEF18NM_0153182.20Rho/Rac guanine nucleotide exchange factor 18
BBC3NM_014417−2.18BCL2 binding component 3 isoform 1
GSNNM_1982525.02Gelsolin isoform c
LGALS1NM_0331012.58Galectin-1
NFKB1NM_003998−3.33Nuclear factor kappa-B, subunit 1 isoform 1
SH3GLB1NM_0160092.82SH3-containing protein SH3GLB1
POLR2GNM_0026962.02DNA directed RNA polymerase II polypeptide G
DDIT4NM_019058−2.23Homo sapiens DNA-damage-inducible transcript 4
STEAP3NM_182915−2.52Dudulin 2 isoform a
DRAM1NM_0183702.29DNA-damage regulated autophagy modulator 1
RNF130NM_0184342.07Ring finger protein 130 precursor
AVENNM_020371−2.62Cell death regulator Aven
TRIB3NM_021158−2.19Tribbles 3
BAXNM_1387642.06BCL2-associated X protein isoform beta
BIDNM_197966−2.76BH3 interacting domain death agonist isoform 1
PERPNM_0221219.42PERP, TP53 apoptosis effector
SPTAN1NM_0031272.63Spectrin, alpha, nonerythrocytic 1
BUB1BNM_001211−2.20Budding uninhibited by benzimidazoles 1 beta
VDAC1NM_003374−2.37Voltage-dependent anion channel 1
BCL2L12NM_1386392.19BCL2-like 12 isoform 1
CUL1NM_003592−2.08Cullin 1
YARSNM_001040436−2.30Tyrosyl-TRNA synthetase
TNFSF9NM_0038112.38Tumor necrosis factor (ligand) superfamily
IER3NM_0038972.17Immediate early response 3
ARHGEF2NM_004723−2.10Rho/Rac guanine nucleotide exchange factor 2
TP53INP1NM_0332853.03Tumor protein p53 inducible nuclear protein 1
ITM2BNM_0219992.32Integral membrane protein 2B
LITAFNM_0048622.25Lipopolysaccharide-induced TNF-alpha factor
ESPL1NM_012291−2.11Separase

−: indicate downregulation.