Peroxisome Proliferator-Activated Receptors in Regulation of Cytochromes P450: New Way to Overcome Multidrug Resistance?

<table>Conversion of arachidonic acid to EETs. Arachidonic acid is released from membrane phospholipids by phospholipase A2. CYP epoxygenases (CYP2C and CYP2J) convert AA into four regioisomeric EETs.</table>

BioMed Research International

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Figure 1

Figure 1: Peroxisome Proliferator-Activated Receptors in Regulation of Cytochromes P450: New Way to Overcome Multidrug Resistance? 