- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 657942, 15 pages
EhADH112 Is a Bro1 Domain-Containing Protein Involved in the Entamoeba histolytica Multivesicular Bodies Pathway
1Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, 07360 México, DF, Mexico
2Centro de Diagnóstico y Vigilancia Epidemiológica del Distrito Federal, Instituto de Ciencia y Tecnología del Distrito Federal, 06010 México, DF, Mexico
3Escuela Superior de Medicina, Instituto Politécnico Nacional, 11340 México, DF, Mexico
4Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC-UAM, 28029 Madrid, Spain
5Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, 03100 México, DF, Mexico
Received 16 July 2011; Accepted 3 October 2011
Academic Editor: Luis I. Terrazas
Copyright © 2012 Cecilia Bañuelos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. L. Stanley Jr., “Amoebiasis,” The Lancet, vol. 361, no. 9362, pp. 1025–1034, 2003.
- R. C. Laughlin and L. A. Temesvari, “Cellular and molecular mechanisms that underlie Entamoeba histolytica pathogenesis: prospects for intervention,” Expert Reviews in Molecular Medicine, vol. 7, no. 13, pp. 1–19, 2005.
- E. Orozco, G. Guarneros, A. Martínez-Palomo, and T. Sánchez, “Entamoeba histolytica. Phagocytosis as a virulence factor,” Journal of Experimental Medicine, vol. 158, no. 5, pp. 1511–1521, 1983.
- M. A. Rodríguez and E. Orozco, “Isolation and characterization of phagocytosis- and virulence-deficient mutants of Entamoeba histolytica,” Journal of Infectious Diseases, vol. 154, no. 1, pp. 27–32, 1986.
- P. F. P. Pimenta, L. S. Diamond, and D. Mirelman, “Entamoeba histolytica Schaudinn, 1903 and Entamoeba dispar Brumpt, 1925: differences in their cell surfaces and in the bacteria-containing vacuoles,” Journal of Eukaryotic Microbiology, vol. 49, no. 3, pp. 209–219, 2002.
- G. García-Rivera, M. A. Rodríguez, R. Ocádiz et al., “Entamoeba histolytica: a novel cysteine protease and an adhesin form the 112 kDa surface protein,” Molecular Microbiology, vol. 33, no. 3, pp. 556–568, 1999.
- C. Bañuelos, G. García-Rivera, I. López-Reyes, and E. Orozco, “Functional characterization of EhADH112: an Entamoeba histolytica Bro1 domain-containing protein,” Experimental Parasitology, vol. 110, no. 3, pp. 292–297, 2005.
- P. Vito, L. Pellegrini, C. Guiet, and L. D'Adamio, “Cloning of AIP1, a novel protein that associates with the apoptosis- linked gene ALG-2 in a Ca2+-dependent reaction,” Journal of Biological Chemistry, vol. 274, no. 3, pp. 1533–1540, 1999.
- M. Missotten, A. Nichols, K. Rieger, and R. Sadoul, “Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein,” Cell Death and Differentiation, vol. 6, no. 2, pp. 124–129, 1999.
- M. H. H. Schmidt, D. Hoeller, J. Yu et al., “Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex,” Molecular and Cellular Biology, vol. 24, no. 20, pp. 8981–8993, 2004.
- M. H. H. Schmidt, I. Dikic, and O. Bögler, “Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities,” Journal of Biological Chemistry, vol. 280, no. 5, pp. 3414–3425, 2005.
- D. J. Katzmann, G. Odorizzi, and S. D. Emr, “Receptor downregulation and multivesicular-body sorting,” Nature Reviews Molecular Cell Biology, vol. 3, no. 12, pp. 893–905, 2002.
- K. Katoh, H. Shibata, H. Suzuki et al., “The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting,” Journal of Biological Chemistry, vol. 278, no. 40, pp. 39104–39113, 2003.
- H. Matsuo, J. Chevallier, N. Mayran et al., “Role of LBPA and Alix in multivesicular liposome formation and endosome organization,” Science, vol. 303, no. 5657, pp. 531–534, 2004.
- S. Pan, R. Wang, X. Zhou et al., “Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly,” EMBO Journal, vol. 27, no. 15, pp. 2077–2090, 2008.
- A. Cabezas, K. G. Bache, A. Brech, and H. Stenmark, “Alix regulates cortical actin and the spatial distribution of endosomes,” Journal of Cell Science, vol. 118, no. 12, pp. 2625–2635, 2005.
- S. Pan, R. Wang, X. Zhou et al., “Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly,” Journal of Biological Chemistry, vol. 281, no. 45, pp. 34640–34650, 2006.
- X. Zhou, J. Si, J. Corvera, G. E. Gallick, and J. Kuang, “Decoding the intrinsic mechanism that prohibits ALIX interaction with ESCRT and viral proteins,” Biochemical Journal, vol. 432, no. 3, pp. 525–534, 2010.
- J. Kim, S. Sitaraman, A. Hierro, B. M. Beach, G. Odorizzi, and J. H. Hurley, “Structural basis for endosomal targeting by the Bro1 domain,” Developmental Cell, vol. 8, no. 6, pp. 937–947, 2005.
- R. D. Fisher, H. Y. Chung, Q. Zhai, H. Robinson, W. I. Sundquist, and C. P. Hill, “Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding,” Cell, vol. 128, no. 5, pp. 841–852, 2007.
- R. E. DeJournett, R. Kobayashi, S. Pan et al., “Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins,” Biochemical Journal, vol. 401, no. 2, pp. 521–531, 2007.
- G. Odorizzi, “The multiple personalities of Alix,” Journal of Cell Science, vol. 119, no. 15, pp. 3025–3032, 2006.
- J. H. Rothman, I. Howald, and T. H. Stevens, “Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae,” EMBO Journal, vol. 8, no. 7, pp. 2057–2065, 1989.
- M. E. Nickas and M. P. Yaffe, “BRO1, a novel gene that interacts with components of the Pkc1p-mitogen-activated protein kinase pathway in Saccharomyces cerevisiae,” Molecular and Cellular Biology, vol. 16, no. 6, pp. 2585–2593, 1996.
- P. I. Hanson, S. Shim, and S. A. Merrill, “Cell biology of the ESCRT machinery,” Current Opinion in Cell Biology, vol. 21, no. 4, pp. 568–574, 2009.
- I. Roxrud, H. Stenmark, and L. Malerød, “ESCRT & Co,” Biology of the Cell, vol. 102, no. 5, pp. 293–318, 2010.
- I. López-Reyes, G. García-Rivera, C. Bañuelos et al., “Detection of the endosomal sorting complex required for transport in Entamoeba histolytica and characterization of the EhVps4 protein,” Journal of Biomedicine and Biotechnology, vol. 2010, Article ID 890674, 2010.
- M. Okada, C. D. Huston, M. Oue et al., “Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis,” Molecular and Biochemical Parasitology, vol. 145, no. 2, pp. 171–183, 2006.
- A. Bateman, E. Birney, L. Cerruti et al., “The pfam protein families database,” Nucleic Acids Research, vol. 30, no. 1, pp. 276–280, 2002.
- L. S. Diamond, D. R. Harlow, and C. C. Cunnick, “A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba,” Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 72, no. 4, pp. 431–432, 1978.
- T. P. Hopp and K. R. Woods, “Prediction of protein antigenic determinants from amino acid sequences,” Proceedings of the National Academy of Sciences of the United States of America, vol. 78, no. 6 I, pp. 3824–3828, 1981.
- L. Hamann, R. Nickel, and E. Tannich, “Transfection and continuous expression of heterologous genes in the protozoan parasite Entamoeba histolytica,” Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 19, pp. 8975–8979, 1995.
- G. García-Rivera, T. Sánchez, E. Orozco, and G. Guarneros, “Isolation of Entamoeba histolytica clones deficient in adhision to human erythrocytes,” Archivos de Investigacion Medica, vol. 13, no. 3, pp. 129–136, 1982.
- S. B. Aley, W. A. Scott, and Z. A. Cohn, “Plasma membrane of Entamoeba histolytica,” Journal of Experimental Medicine, vol. 152, no. 2, pp. 391–404, 1980.
- O. Vincent, L. Rainbow, J. Tilburn, H. N. Arst, and M. A. Peñalva, “YPXL/I is a protein interaction motif recognized by Aspergillus PalA and its human homologue, AIP1/Alix,” Molecular and Cellular Biology, vol. 23, no. 5, pp. 1647–1655, 2003.
- W. Xu, F. J. Smith Jr., R. Subaran, and A. P. Mitchell, “Multivesicular body-ESCRT components function in pH response regulation in Saccharomyces cerevisiae and Candida albicans,” Molecular Biology of the Cell, vol. 15, no. 12, pp. 5528–5537, 2004.
- F. Ichioka, R. Kobayashi, K. Katoh, H. Shibata, and M. Maki, “Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4),” FEBS Journal, vol. 275, no. 4, pp. 682–692, 2008.
- C. Martínez-López, E. Orozco, T. Sánchez, R. M. García-Pérez, F. Hernández-Hernández, and M. A. Rodríguez, “The EhADH112 recombinant polypeptide inhibits cell destruction and liver abscess formation by Entamoeba histolytica trophozoites,” Cellular Microbiology, vol. 6, no. 4, pp. 367–376, 2004.
- M. Babst, “A protein's final ESCRT,” Traffic, vol. 6, no. 1, pp. 2–9, 2005.
- N. Bishop and P. Woodman, “ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking,” Molecular Biology of the Cell, vol. 11, no. 1, pp. 227–239, 2000.
- N. Luhtala and G. Odorizzi, “Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes,” Journal of Cell Biology, vol. 166, no. 5, pp. 717–729, 2004.
- K. Denzer, M. J. Kleijmeer, H. F. G. Heijnen, W. Stoorvogel, and H. J. Geuze, “Exosome: from internal vesicle of the multivesicular body to intercellular signaling device,” Journal of Cell Science, vol. 113, no. 19, pp. 3365–3374, 2000.
- G. Odorizzi, D. J. Katzmann, M. Babst, A. Audhya, and S. D. Emr, “Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae,” Journal of Cell Science, vol. 116, no. 10, pp. 1893–1903, 2003.
- J. Gruenberg and H. Stenmark, “The biogenesis of multivesicular endosomes,” Nature Reviews Molecular Cell Biology, vol. 5, no. 4, pp. 317–323, 2004.
- U. K. Von Schwedler, M. Stuchell, B. Müller et al., “The protein network of HIV budding,” Cell, vol. 114, no. 6, pp. 701–713, 2003.
- J. H. Boysen and A. P. Mitchell, “Control of Bro1-domain protein Rim20 localization by external pH, ESCRT machinery, and the Saccharomyces cerevisiae Rim101 pathway,” Molecular Biology of the Cell, vol. 17, no. 3, pp. 1344–1353, 2006.
- J. McCullough, R. D. Fisher, F. G. Whitby, W. I. Sundquist, and C. P. Hill, “ALIX-CHMP4 interactions in the human ESCRT pathway,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 22, pp. 7687–7691, 2008.
- T. Irie, N. Nagata, T. Yoshida, and T. Sakaguchi, “Recruitment of Alix/AIP1 to the plasma membrane by Sendai virus C protein facilitates budding of virus-like particles,” Virology, vol. 371, no. 1, pp. 108–120, 2008.