Table 1: Transversal stiffness (pN/nm) of isolated rat’s Triton-treated left ventricular myocytes in liquid in relaxed, calcium activated (pCa = 4.2) and rigor states under gravitational unloading and subsequent reloading.

State
GroupRelaxedActivated (pCa = 4.2)Rigor

Transversal stiffness of the half-sarcomere area 𝑘 c a
Control ( 𝑛 = 1 6 5 )7.1 ± 0.411.0 ± 0.5@13.2 ± 0.5@
1-HS ( 𝑛 = 1 5 3 )6.8 ± 0.310.3 ± 0.3@12.9 ± 0.3@
3-HS ( 𝑛 = 1 4 9 )8.2 ± 0.3*13.8 ± 0.4*/@14.7 ± 0.3*/@
7-HS ( 𝑛 = 1 4 8 )8.9 ± 0.3*13.5 ± 0.3*/@15.3 ± 0.3*/@
14-HS ( 𝑛 = 1 5 7 )8.7 ± 0.4*13.6 ± 0.4*/@15.6 ± 0.4*/@
14-HS + 3-R ( 𝑛 = 1 6 2 )4.3 ± 0.3*/$6.8 ± 0.3*/@/$8.2 ± 0.5*/@/$
14-HS + 7-R ( 𝑛 = 1 5 1 )7.7 ± 0.311.0 ± 0.9@13.4 ± 0.6@

Transversal stiffness of the M-band area 𝑘 m l
Control9.9 ± 0.615.0 ± 0.6@16.4 ± 0.5@
1-HS8.9 ± 0.514.1 ± 0.4@15.8 ± 0.5@
3-HS9.3 ± 0.514.8 ± 0.6@16.3 ± 0.5@
7-HS10.6 ± 0.414.9 ± 0.5@16.5 ± 0.8@
14-HS9.8 ± 0.514.2 ± 0.6@15.7 ± 0.3@
14-HS + 3-R6.2 ± 0.3*/$12.6 ± 0.4*/@/$13.1 ± 0.4*/@/$
14-HS + 7-R9.3 ± 0.414.3 ± 0.8@17.1 ± 0.5@

Transversal stiffness of the Z-disk area 𝑘 Z d
Control16.0 ± 1.322.5 ± 1.5@24.5 ± 0.9@
1-HS15.4 ± 0.621.6 ± 0.3@24.8 ± 0.6@
3-HS15.9 ± 0.623.4 ± 0.7@26.1 ± 1.3@
7-HS15.9 ± 0.521.7 ± 0.3@25.9 ± 0.6@
14-HS15.8 ± 0.821.9 ± 0.9@22.9 ± 0.7@
14-HS + 3-R7.5 ± 0.4*/$13.4 ± 0.5*/@/$16.0 ± 0.4*/@/$
14-HS + 7-R15.4 ± 0.621.4 ± 0.5@23.4 ± 1.4@

𝑃 < 0 . 0 5 as compared to the analogous state of the group “Control”, @ 𝑃 < 0 . 0 5 as compared to the relaxed state at the same group, $ 𝑃 < 0 . 0 5 as compared to the analogous state of the group “14-HS”.