About this Journal Submit a Manuscript Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 672416, 7 pages
http://dx.doi.org/10.1155/2012/672416
Research Article

Antiproliferative and Anti-Invasive Effect of Piceatannol, a Polyphenol Present in Grapes and Wine, against Hepatoma AH109A Cells

1Department of Applied Biological Chemistry, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan
2Division of Applied Biological Chemistry, Institue of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan

Received 6 September 2011; Accepted 11 October 2011

Academic Editor: Masa-Aki Shibata

Copyright © 2012 Yuichiro Kita et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. A. Liotta, U. Wewer, N. C. Rao et al., “Biochemical mechanisms of tumor invasion and metastases,” Progress in Clinical and Biological Research, vol. 256, pp. 3–16, 1988. View at Scopus
  2. G. Zhang, Y. Miura, and K. Yagasaki, “Effects of green, oolong and black teas and related components on the proliferation and invasion of hepatoma cells in culture,” Cytotechnology, vol. 31, no. 1-2, pp. 37–44, 1999. View at Scopus
  3. G. Zhang, Y. Miura, and K. Yagasaki, “Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas,” Nutrition and Cancer, vol. 38, no. 2, pp. 265–273, 2000. View at Scopus
  4. G. Zhang, Y. Miura, and K. Yagasaki, “Suppression of adhesion and invasion of hepatoma cells in culture by tea compounds through antioxidative activity,” Cancer Letters, vol. 159, no. 2, pp. 169–173, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Miura, N. M. Saarinen, Y. Miura, R. Santti, and K. Yagasaki, “Hydroxymatairesinol and its mammalian metabolite enterolactone reduce the growth and metastasis of subcutaneous AH109A hepatomas in rats,” Nutrition and Cancer, vol. 58, no. 1, pp. 49–59, 2007. View at Scopus
  6. M. Jang, L. Cai, G. O. Udeani et al., “Cancer chemopreventive activity of resveratrol, a natural product derived from grapes,” Science, vol. 275, no. 5297, pp. 218–220, 1997. View at Scopus
  7. T. C. Hsieh, P. Burfeind, K. Laud et al., “Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials,” International Journal of Oncology, vol. 15, no. 2, pp. 245–252, 1999. View at Scopus
  8. Y. Kozuki, Y. Miura, and K. Yagasaki, “Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action,” Cancer Letters, vol. 167, no. 2, pp. 151–156, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Miura, Y. Miura, and K. Yagasaki, “Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property,” Clinical and Experimental Metastasis, vol. 21, no. 5, pp. 445–451, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Larrosa, F. A. Tomás-Barberán, and J. C. Espín, “The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells,” European Journal of Nutrition, vol. 43, no. 5, pp. 275–284, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Yagihashi, Y. Miura, and K. Yagasaki, “Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture,” Cytotechnology, vol. 57, no. 2, pp. 129–136, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Akedo, K. Shinkai, M. Mukai, et al., “Interaction of rat ascites hepatoma cells with cultured mesothelial cell layers: a model for tumor invasion,” Cancer Research, vol. 46, no. 5, pp. 2416–2422, 1986.
  13. Y. Miura, H. Shiomi, F. Sakai, and K. Yagasaki, “Assay systems for screening food components that have anti-proliferative and anti-invasive activity to rat ascites hepatoma cells: in vitro and ex vivo effects of green tea extract,” Cytotechnology, vol. 23, no. 1–3, pp. 127–132, 1997. View at Scopus
  14. Y. Miura, K. Ono, R. Okauchi, and K. Yagasaki, “Inhibitory effect of coffee on hepatoma proliferation and invasion in culture and on tumor growth, metastasis and abnormal lipoprotein profiles in hepatoma-bearing rats,” Journal of Nutritional Science and Vitaminology, vol. 50, no. 1, pp. 38–44, 2004. View at Scopus
  15. D. A. Bass, J. W. Parce, L. R. Dechatelet, P. Szejda, M. C. Seeds, and M. Thomas, “Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation,” Journal of Immunology, vol. 130, no. 4, pp. 1910–1917, 1983.
  16. Y. Miura, Y. Kozuki, and K. Yagasaki, “Potentiation of invasive activity of hepatoma cells by reactive oxygen species is mediated by autocrine/paracrine loop of hepatocyte growth factor,” Biochemical and Biophysical Research Communications, vol. 305, no. 1, pp. 160–165, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. Kozuki, Y. Miura, and K. Yagasaki, “Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture,” Cancer Letters, vol. 151, no. 1, pp. 111–115, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. C. Parr and W. G. Jiang, “Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells,” International Journal of Oncology, vol. 19, no. 4, pp. 857–863, 2001. View at Scopus