Profiling of Age-Related Changes in the Tibialis Anterior Muscle Proteome of the mdx Mouse Model of Dystrophinopathy

Table 2

List of identified proteins that exhibit a drastic change in abundance during aging of the dystrophic mdx tibialis anterior muscle.

Spot No.	Protein name	Accession No.	Isoelectric point (pI)	Molecular mass (Da)	Number of peptides	Coverage	Mascot	Fold change 8w-22 m
						(%)	Score
1	Carbonic anhydrase CA3	NP031632	6.89	29,638	4	26	181	2.9
2	Aldolase A isoform 2	NP031464	8.31	39,795	2	14	85	2.3
3	Electron transferring flavoprotein, beta	EDL22660	8.50	29,177	13	42	190	1.9
4	Carbonic anhydrase CA3	NP031632	6.89	29,638	12	53	182	1.7
5	Pyruvate kinase	NP035229	7.18	58,388	7	18	440	0.7
6	Myosin 3	NP001078847	5.62	224,755	9	5	141	0.7
7	Tropomyosin, beta chain	NP033442	4.66	32,933	3	14	126	0.6
8	Heat shock protein Hsp27	AAA18335	6.45	22,945	2	15	55	0.5