About this Journal Submit a Manuscript Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 692609, 11 pages
http://dx.doi.org/10.1155/2012/692609
Review Article

Animal Models of Glaucoma

1Department of Ophthalmology, Summa Health System, Akron, OH 44304, USA
2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21210, USA
3Research Department, King Khaled Eye Specialist Hospital, P.O. Box 7191, Riyadh 11462, Saudi Arabia

Received 16 January 2012; Revised 27 February 2012; Accepted 29 February 2012

Academic Editor: Monica Fedele

Copyright © 2012 Rachida A. Bouhenni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [37 citations]

The following is the list of published articles that have cited the current article.

  • Ankur Gupta, “Leptin as a Neuroprotective agent in Glaucoma,” Medical Hypotheses, 2013. View at Publisher · View at Google Scholar
  • K Namekata, A Kimura, K Kawamura, X Guo, C Harada, K Tanaka, and T Harada, “Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma,” Cell Death and Differentiation, 2013. View at Publisher · View at Google Scholar
  • Mike O. Karl, “The potential of stem cell research for the treatment of neuronal damage in glaucoma,” Cell and Tissue Research, 2013. View at Publisher · View at Google Scholar
  • Caroline J. Zeiss, “Translational models of ocular disease,” Veterinary Ophthalmology, vol. 16, pp. 15–33, 2013. View at Publisher · View at Google Scholar
  • LaKisha K. Buie, Md. Zahidul Karim, Matthew H. Smith, and Teresa Borrás, “Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2,” Investigative Ophthalmology and Visual Science, vol. 54, no. 8, pp. 5441–5455, 2013. View at Publisher · View at Google Scholar
  • Ying Hu, Hai Bo Tan, Xin Mei Wang, Hua Rong, Hong Ping Cui, and Hao Cui, “Bone marrow mesenchymal stem cells protect against retinal ganglion cell loss in aged rats with glaucoma,” Clinical Interventions in Aging, vol. 8, pp. 1467–1470, 2013. View at Publisher · View at Google Scholar
  • Chang Tan, Tu Hu, Ming-chao Peng, Shu-li Liu, Jian-bin Tong, Wen Ouyang, and Yuan Le, “Age of Rats Seriously Affects the Degree of Retinal Damage Induced by Acute High Intraocular Pressure,” Current Eye Research, pp. 1–7, 2014. View at Publisher · View at Google Scholar
  • L. Ramm, S. Jentsch, S. Peters, R. Augsten, and M. Hammer, “Investigation of blood flow regulation and oxygen saturation of the retinal vessels in primary open-angle glaucoma,” Graefe's Archive for Clinical and Experimental Ophthalmology, 2014. View at Publisher · View at Google Scholar
  • K Semba, K Namekata, X Guo, C Harada, T Harada, and Y Mitamura, “Renin–angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma,” Cell Death and Disease, vol. 5, no. 7, pp. e1333, 2014. View at Publisher · View at Google Scholar
  • Cula N. Dautriche, Yubing Xie, and Susan T. Sharfstein, “Walking through Trabecular Meshwork Biology: Towards Engineering Design of Outflow Physiology,” Biotechnology Advances, 2014. View at Publisher · View at Google Scholar
  • Hamidreza Riazifar, Yousheng Jia, Jing Chen, Gary Lynch, and Taosheng Huang, “Chemically Induced Specification of Retinal Ganglion Cells From Human Embryonic and Induced Pluripotent Stem Cells,” Stem Cells Translational Medicine, vol. 3, no. 4, pp. 424–432, 2014. View at Publisher · View at Google Scholar
  • Lies De Groef, Inge Van Hove, Eline Dekeyster, Ingeborg Stalmans, and Lieve Moons, “MMPs in the Neuroretina and Optic Nerve: Modulators of Glaucoma Pathogenesis and Repair?,” Investigative Ophthalmology & Visual Science, vol. 55, no. 3, pp. 1953–1964, 2014. View at Publisher · View at Google Scholar
  • Sara McNally, and Colm J. O’Brien, “Drug discovery in glaucoma and the role of animal models,” Drug Discovery Today: Disease Models, 2014. View at Publisher · View at Google Scholar
  • Marcus Karlstetter, Rebecca Scholz, Matt Rutar, Wai T. Wong, Jan M. Provis, and Thomas Langmann, “Retinal Microglia: Just Bystander or Target for Therapy ?,” Progress in Retinal and Eye Research, 2014. View at Publisher · View at Google Scholar
  • Adan Villamarin, Nikos Stergiopulos, Stephane Bigler, Andre Mermoud, Alexandre Moulin, and Sylvain Roy, “In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device,” Investigative Ophthalmology & Visual Science, vol. 55, no. 11, pp. 7520–7524, 2014. View at Publisher · View at Google Scholar
  • Oliver W. Gramlich, Theresa C. S. Lueckner, Maren Kriechbaum, Julia Teister, Xue Tao, Harald D. von Pein, Norbert Pfeiffer, and Franz H. Grus, “Dynamics, Alterations, and Consequences of Minimally Invasive Intraocular Pressure Elevation in Rats,” Investigative Ophthalmology & Visual Science, vol. 55, no. 1, pp. 600–611, 2014. View at Publisher · View at Google Scholar
  • Rebecca K. Donegan, and Raquel L. Lieberman, “Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions,” Journal of Medicinal Chemistry, pp. 150925104901003, 2015. View at Publisher · View at Google Scholar
  • A I Iglesias, H Springelkamp, W D Ramdas, C C W Klaver, R Willemsen, and C M van Duijn, “Genes, pathways, and animal models in primary open-angle glaucoma,” Eye, 2015. View at Publisher · View at Google Scholar
  • Hsin-Hua Liu, Bang V. Bui, Christine T. O. Nguyen, Jelena M. Kezic, Algis J. Vingrys, and Zheng He, “Chronic Ocular Hypertension Induced by Circumlimbal Suture in Rats,” Investigative Ophthalmology & Visual Science, vol. 56, no. 5, pp. 2811–2820, 2015. View at Publisher · View at Google Scholar
  • Lisa Ramm, Susanne Jentsch, Sven Peters, Lydia Sauer, Regine Augsten, and Martin Hammer, “Dependence of diameters and oxygen saturation of retinal vessels on visual field damage and age in primary open-angle glaucoma,” Acta Ophthalmologica, 2015. View at Publisher · View at Google Scholar
  • Janice A. Vranka, Mary J. Kelley, Ted S. Acott, and Kate E. Keller, “Extracellular matrix in the trabecular meshwork: Intraocular pressure regulation and dysregulation in glaucoma,” Experimental Eye Research, vol. 133, pp. 112–125, 2015. View at Publisher · View at Google Scholar
  • Nidhi Agarwal, Daren Hanumunthadu, Morteza Afrasiabi, Giulia Malaguarnera, and Maria Francesca Cordeiro, “Clinical update in optic nerve disorders,” Expert Review of Ophthalmology, pp. 1–22, 2015. View at Publisher · View at Google Scholar
  • Rana N. El-Danaf, and Andrew D. Huberman, “Characteristic Patterns of Dendritic Remodeling in Early-Stage Glaucoma: Evidence from Genetically Identified Retinal Ganglion Cell Types,” Journal Of Neuroscience, vol. 35, no. 6, pp. 2329–2343, 2015. View at Publisher · View at Google Scholar
  • Zhichao Yan, Zhen Tian, Hongrui Chen, Shuifeng Deng, Jianxian Lin, Huanquan Liao, Xuejiao Yang, Jian Ge, and Yehong Zhuo, “Analysis of a method for establishing a model with more stable chronic glaucoma in rhesus monkeys,” Experimental Eye Research, vol. 131, pp. 56–62, 2015. View at Publisher · View at Google Scholar
  • Ning-Jiun Jan, Jonathan L. Grimm, Huong Tran, Kira L. Lathrop, Gadi Wollstein, Richard A. Bilonick, Hiroshi Ishikawa, Larry Kagemann, Joel S. Schuman, and Ian A. Sigal, “Polarization microscopy for characterizing fiber orientation of ocular tissues,” Biomedical Optics Express, vol. 6, no. 12, pp. 4705, 2015. View at Publisher · View at Google Scholar
  • Hao Li, Wenzhong Liu, and Hao F. Zhang, “Investigating the influence of chromatic aberration and optical illumination bandwidth on fundus imaging in rats,” Journal Of Biomedical Optics, vol. 20, no. 10, 2015. View at Publisher · View at Google Scholar
  • Wenwen Wang, Guowei Zhang, Hui Gu, Ye Liu, Jifeng Lao, Kuifang Li, and Huaijin Guan, “Role of CtBP2 in the Apoptosis of Retinal Ganglion Cells,” Cellular and Molecular Neurobiology, 2015. View at Publisher · View at Google Scholar
  • Makoto Ishikawa, Takeshi Yoshitomi, Charles F. Zorumski, and Yukitoshi Izumi, “Experimentally Induced Mammalian Models of Glaucoma,” BioMed Research International, vol. 2015, pp. 1–11, 2015. View at Publisher · View at Google Scholar
  • Nobuyuki Kanemaki, Yoichiro Ichikawa, Shinpei Kawarai, and Hideharu Ochiai, “Classification of Clinical Findings of Glaucoma in Dogs Presenting at the Ophthalmic Department of Azabu Veterinary Teaching Hospital,” Journal of the Japan Veterinary Medical Association, vol. 68, no. 1, pp. 55–58, 2015. View at Publisher · View at Google Scholar
  • HaiBo Tan, Xin Kang, ShiHeng Lu, and Lin Liu, “The therapeutic effects of bone marrow mesenchymal stem cells after optic nerve damage in the adult rat,” Clinical Interventions In Aging, vol. 10, pp. 487–490, 2015. View at Publisher · View at Google Scholar
  • Liwen Chen, Yin Zhao, and Hong Zhang, “Comparative Anatomy of the Trabecular Meshwork, the Optic Nerve Head and the Inner Retina in Rodent and Primate Models Used for Glaucoma Research,” Vision, vol. 1, no. 1, pp. 4, 2016. View at Publisher · View at Google Scholar
  • Lin Liu, Qinglei Sun, Ruobing Wang, Zeli Chen, Jiangchun Wu, Fangzhou Xia, and Xian-qun Fan, “Methane attenuates retinal ischemia/reperfusion injury via anti-oxidative and anti-apoptotic pathways,” Brain Research, 2016. View at Publisher · View at Google Scholar
  • Yoko A. Ito, Nicolas Belforte, Jorge L. Cueva Vargas, and Adriana Di Polo, “A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice,” Jove-Journal Of Visualized Experiments, no. 109, 2016. View at Publisher · View at Google Scholar
  • Stanislava Fialová, Marco Augustin, Martin Glösmann, Tanja Himmel, Sabine Rauscher, Marion Gröger, Michael Pircher, Christoph K. Hitzenberger, and Bernhard Baumann, “Polarization properties of single layers in the posterior eyes of mice and rats investigated using high resolution polarization sensitive optical coherence tomography,” Biomedical Optics Express, vol. 7, no. 4, pp. 1479, 2016. View at Publisher · View at Google Scholar
  • Silke Becker, Karen Eastlake, Hari Jayaram, Megan F. Jones, Robert A. Brown, Gillian J. McLellan, David G. Charteris, Peng T. Khaw, and G. Astrid Limb, “Allogeneic Transplantation of Muller-Derived Retinal Ganglion Cells Improves Retinal Function in a Feline Model of Ganglion Cell Depletion,” Stem Cells Translational Medicine, vol. 5, no. 2, pp. 192–205, 2016. View at Publisher · View at Google Scholar
  • Nicholas J. D. Gower, Robert J. Barry, Matthew R. Edmunds, Lucy C. Titcomb, and Alastair K. Denniston, “Drug discovery in ophthalmology: past success, present challenges, and future opportunities,” BMC Ophthalmology, vol. 16, no. 1, 2016. View at Publisher · View at Google Scholar
  • Evgeni Y. Zernii, Viktoriia E. Baksheeva, Elena N. Iomdina, Olga A. Averina, Sergei E. Permyakov, Pavel P. Philippov, Andrey A. Zamyatnin, and Ivan I. Senin, “Rabbit Models of Ocular Diseases: New Relevance for Classical Approaches,” Cns & Neurological Disorders-Drug Targets, vol. 15, no. 3, pp. 267–291, 2016. View at Publisher · View at Google Scholar