- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 695843, 11 pages
Plasmodium Riboprotein PfP0 Induces a Deviant Humoral Immune Response in Balb/c Mice
1Malarial Parasite Biology Laboratory, Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India
2Bioklone, Chennai 600061, India
3Department of Oncology, The Sidney Kimmel Comprehensive Cancer Centre, Johns Hopkins Medical Institute, Baltimore, MD 21231, USA
4Department of Medicine, SCB Medical College Hospital, Cuttack 753007, India
5Basic and Clinical Immunology of Parasitic diseases Group, Centre for Infection and Immunity of Lille, 59019 Lille Cedex, France
6Infectious Disease Biology Group, Institute of Life Sciences, Bhubaneswar 751023, India
Received 5 July 2011; Revised 30 September 2011; Accepted 2 October 2011
Academic Editor: Jorge Morales-Montor
Copyright © 2012 Sulabha Pathak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- B. E. Rich and J. A. Steitz, “Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly,” Molecular and Cellular Biology, vol. 7, no. 11, pp. 4065–4074, 1987.
- M. T. Saenz-Robles, M. Remacha, M. D. Vilella, S. Zinker, and J. P. G. Ballesta, “The acidic ribosomal proteins as regulators of the eukaryotic ribosomal activity,” Biochimica et Biophysica Acta, vol. 1050, no. 1–3, pp. 51–55, 1990.
- T. Uchiumi, A. J. Wahha, and R. R. Traut, “Topography and stoichiometry of acidic proteins in large ribosomal subunits from Artemia salina as determined by cross linking,” Proceedings of the National Academy of Sciences of United States of America, vol. 84, no. 16, pp. 5580–5584, 1987.
- T. Uchiumi and R. Kominami, “Direct evidence for interaction of the conserved GTPase domain within 28 S RNA with mammalian ribosomal acidic phosphoproteins and L12,” Journal of Biological Chemistry, vol. 267, no. 27, pp. 19179–19185, 1992.
- C. Santos and J. P. G. Ballesta, “Ribosomal protein P0, contrary to phosphoproteins P1 and P2, is required for ribosome activity and Saccharomyces cerevisiae viability,” Journal of Biological Chemistry, vol. 269, no. 22, pp. 15689–15696, 1994.
- S. Das, H. Basu, R. Korde, et al., “Arrest of nuclear division in Plasmodium through blockage of erythrocyte surface exposed ribosomal protein P2,” In press.
- A. Yacoub, M. R. Kelley, and W. A. Deutsch, “Drosophila ribosomal protein PO contains apurinic/apyrimidinic endonuclease activity,” Nucleic Acids Research, vol. 24, no. 21, pp. 4298–4303, 1996.
- M. V. Frolov and J. A. Birchler, “Mutation in P0, a dual function ribosomal protein/apurinic/apyrimidinic endonuclease, modifies gene expression and position effect variegation in Drosophila,” Genetics, vol. 150, no. 4, pp. 1487–1495, 1998.
- E. Brockstedt, A. Rickers, S. Kostka et al., “Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line: cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3,” Journal of Biological Chemistry, vol. 273, no. 43, pp. 28057–28064, 1998.
- N. Kondoh, T. Wakatsuki, R. Akihide et al., “Identification and characterization of genes associated with human hepatocellular carcinogenesis,” Cancer Research, vol. 59, no. 19, pp. 4990–4996, 1999.
- S. Singh, A. Sehgal, S. Waghmare, T. Chakraborty, A. Goswami, and S. Sharma, “Surface expression of the conserved ribosomal protein P0 on parasite and other cells,” Molecular and Biochemical Parasitology, vol. 119, no. 1, pp. 121–124, 2002.
- S. Hirohata and K. Nakanishi, “Antiribosomal P protein antibody in human systemic lupus erythematosus reacts specifically with activated T cells,” Lupus, vol. 10, no. 9, pp. 612–621, 2001.
- E. Koren, M. W. Reichlin, M. Koscec, R. D. Fugate, and M. Reichlin, “Autoantibodies to the ribosomal P proteins react with a plasma membrane- related target on human cells,” Journal of Clinical Investigation, vol. 89, no. 4, pp. 1236–1241, 1992.
- G. Frampton, S. Moriya, J. D. Pearson et al., “Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: a role for ribosomal P protein PO as an endothelial cell autoantigen,” Rheumatology, vol. 39, no. 10, pp. 1114–1120, 2000.
- A. Goswami, S. Singh, V. D. Redkar, and S. Sharma, “Characterization of P0, a ribosomal phosphoprotein of Plasmodium falciparum. Antibody against amino-terminal domain inhibits parasite growth,” Journal of Biological Chemistry, vol. 272, no. 18, pp. 12138–12143, 1997.
- C. A. Lobo, S. K. Kar, B. Ravindran, L. Kabilan, and S. Sharma, “Novel proteins of Plasmodium falciparum identified by differential immunoscreening using immune and patient sera,” Infection and Immunity, vol. 62, no. 2, pp. 651–656, 1994.
- I. Malhotra, P. Mungai, E. Muchiri et al., “Distinct Th1- and Th2-type prenatal cytokine responses to Plasmodium falciparum erythrocyte invasion ligands,” Infection and Immunity, vol. 73, no. 6, pp. 3462–3470, 2005.
- S. Chatterjee, S. Singh, R. Sohoni et al., “Antibodies against ribosomal phosphoprotein P0 of Plasmodium falciparum protect mice against challenge with Plasmodium yoelii,” Infection and Immunity, vol. 68, no. 7, pp. 4312–4318, 2000.
- K. Rajeshwari, K. Patel, S. Nambeesan et al., “The P domain of the P0 protein of Plasmodium falciparum protects against challenge with malaria parasites,” Infection and Immunity, vol. 72, no. 9, pp. 5515–5521, 2004.
- Rajeshwari and Sharma, Unpublished observation.
- S. Chatterjee, S. Singh, R. Sohoni et al., “Characterization of domains of the phosphoriboprotein P0 of Plasmodium falciparum,” Molecular and Biochemical Parasitology, vol. 107, no. 2, pp. 143–154, 2000.
- K. Aruna, T. Chakraborty, S. Nambeesan et al., “Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0,” Journal of Biosciences, vol. 29, no. 1, pp. 33–43, 2004.
- A. Hofbauer, Eine Bibliothek monoklonaler Antikorper gegen das Gehirn von Drosophila melanogaster, Habilitation thesis, University of Wurzburg, Wurzburg, Germany, 1991.
- B. M. Mony, M. Mehta, G. K. Jarori, and S. Sharma, “Plant-like phosphofructokinase from Plasmodium falciparum belongs to a novel class of ATP-dependent enzymes,” International Journal for Parasitology, vol. 39, no. 13, pp. 1441–1453, 2009.
- I. Pal-Bhowmick, H. K. Vora, J. Roy, S. Sharma, and G. K. Jarori, “Generation and characterisation of monoclonal antibodies specific to Plasmodium falciparum enolase,” Journal of Vector Borne Diseases, vol. 43, no. 2, pp. 43–52, 2006.
- J. V. Frangioni and B. G. Neel, “Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins,” Analytical Biochemistry, vol. 210, no. 1, pp. 179–187, 1993.
- E. Engvall, “Enzyme immunoassay ELISA and EMIT,” Methods in Enzymology, vol. 70, pp. 419–439, 1980.
- M. Claussen, R. Koch, Z. Y. Jin, and B. Suter, “Functional characterization of Drosophila Translin and Trax,” Genetics, vol. 174, no. 3, pp. 1337–1347, 2006.
- A. Fujii, M. Yoneda, T. Ito et al., “Autoantibodies against the amino terminal of α-enolase are a useful diagnostic marker of Hashimoto's encephalopathy,” Journal of Neuroimmunology, vol. 162, no. 1-2, pp. 130–136, 2005.
- A. Magrys, T. Anekonda, G. Ren, and G. Adamus, “The role of anti-α-enolase autoantibodies in pathogenicity of autoimmune-mediated retinopathy,” Journal of Clinical Immunology, vol. 27, no. 2, pp. 181–192, 2007.
- K. L. Calame, “Plasma cells: finding new light at the end of B cell development,” Nature Immunology, vol. 2, no. 12, pp. 1103–1108, 2001.
- C. Bouras, B. M. Riederer, E. Kövari, P. R. Hof, and P. Giannakopoulos, “Humoral immunity in brain aging and Alzheimer's disease,” Brain Research Reviews, vol. 48, no. 3, pp. 477–487, 2005.
- B. Tchernychev, S. Cabilly, and M. Wilchek, “The epitopes for natural polyreactive antibodies are rich in proline,” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 12, pp. 6335–6339, 1997.
- Z. H. Zhou, A. G. Tzioufas, and A. L. Notkins, “Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells,” Journal of Autoimmunity, vol. 29, no. 4, pp. 219–228, 2007.
- A. Berneman, B. Guilbert, S. Eschrich, and S. Avrameas, “IgG auto- and polyreactivities of normal human sera,” Molecular Immunology, vol. 30, no. 16, pp. 1499–1510, 1993.
- M. Bruley-Rosset, L. Mouthon, Y. Chanseaud, F. Dhainaut, J. Lirochon, and D. Bourel, “Polyreactive autoantibodies purified from human intravenous immunoglobulins prevent the development of experimental autoimmune diseases,” Laboratory Investigation, vol. 83, no. 7, pp. 1013–1023, 2003.
- http://PlasmoDB.org, 2011.
- T. Ternynck, P. B. Falanga, C. Unterkirscher, J. Gregoire, L. Pereira da Silva, and S. Avrameas, “Induction of high levels of IgG autoantibodies in mice infected with Plasmodium chabaudi,” International Immunology, vol. 3, no. 1, pp. 29–37, 1991.
- C. T. Daniel-Ribeiro and G. Zanini, “Autoimmunity and malaria: what are they doing together?” Acta Tropica, vol. 76, no. 3, pp. 205–221, 2000.
- C. D. Ribeiro, C. Alfred, L. Monjour, and M. Gentilini, “Normal frequency of anti-thyroglobulin antibodies in hyperendemic areas of malaria: relevance to the understanding of autoantibody formation in malaria,” Tropical and Geographical Medicine, vol. 36, no. 4, pp. 323–328, 1984.
- V. Hurez, G. Dietrich, S. V. Kaveri, and M. D. Kazatchkine, “Polyreactivity is a property of natural and disease-associated human autoantibodies,” Scandinavian Journal of Immunology, vol. 38, no. 2, pp. 190–196, 1993.
- K. A. Siminovitch, V. Misener, P. C. Kwong, Q. L. Song, and P. P. Chen, “A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation,” Journal of Clinical Investigation, vol. 84, no. 5, pp. 1675–1678, 1989.
- I. Sanz, P. Casali, J. W. Thomas, A. L. Notkins, and J. D. Capra, “Nucleotide sequences of eight human natural autoantibody v(H) regions reveals apparent restricted use of V(H) families,” Journal of Immunology, vol. 142, no. 11, pp. 4054–4061, 1989.
- L. C. James, P. Roversi, and D. S. Tawfik, “Antibody multispecificity mediated by conformational diversity,” Science, vol. 299, no. 5611, pp. 1362–1367, 2003.
- D. K. Sethi, A. Agarwal, V. Manivel, K. V. S. Rao, and D. M. Salunke, “Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response,” Immunity, vol. 24, no. 4, pp. 429–438, 2006.
- K. Marsh and S. Kinyanjui, “Immune effector mechanisms in malaria,” Parasite Immunology, vol. 28, no. 1-2, pp. 51–60, 2006.
- B. C. Urban, D. J. P. Ferguson, A. Pain et al., “Plasmodium falciparum infected erythrocytes modulate the maturation of dendritic cells,” Nature, vol. 400, no. 6739, pp. 73–77, 1999.
- S. K. Pierce and L. H. Miller, “World Malaria Day 2009: what malaria knows about the immune system that immunologists still do not,” Journal of Immunology, vol. 182, no. 9, pp. 5171–5177, 2009.
- M. N. Wykes, Y. H. Zhou, X. Q. Liu, and M. F. Good, “Plasmodium yoelii can ablate vaccine-induced long-term protection in mice,” Journal of Immunology, vol. 175, no. 4, pp. 2510–2516, 2005.
- H. Xu, J. Wipasa, H. Yan et al., “The mechanism and significance of deletion of parasite-specific CD4+ T cells in malaria infection,” Journal of Experimental Medicine, vol. 195, no. 7, pp. 881–892, 2002.