704061.fig.003a
(a)
704061.fig.003b
(b)
704061.fig.003c
(c)
704061.fig.003d
(d)
Figure 3: Relationships between global fiber strain and local membrane and sarcomere strain. Raw data (a, c) and regression coefficients (b, d) for (a-b) fiber strain-sarcomere strain; (c-d) membrane strain-sarcomere strain for fibers from 10-month-old wild-type (blue), desmin-null (red), K19-null (orange), and double-null (green) animals ( 𝑛 = 3 fibers/genotype). Different symbols within a color group represent data from individual experiments. Displayed regression lines in (a) and (c) represent averaged coefficients for individual experiments reported in (b) and (d).