Table 3: Hydrogen-bond interaction parameters for each compound with NA and HA receptors.

Sl. no.Residue involvedLigand atom involvedH-bond distance (Å)

Oseltamivir on NA receptor

1ARG109O1.832
2ARG143O2.280
3ARG143O2.407
4GLU219N1.760

B-Sialic on HA receptor

1ALA142O2.137
2ASP230O2.047
3GLN231O2.032
4GLN231O1.965
5GLN231O1.910
6GLU232O2.182
7THR141O2.224
8THR141O1.796

O-Sialic on HA receptor

1ALA142O2.136
2ASP230O1.966
3ASP230O1.928
4GLN231O2.073
5GLN231O1.995
6GLU232O2.217
7THR141O2.215
8THR141O1.830