716023.fig.002a
(a)
716023.fig.002b
(b)
716023.fig.002c
(c)
716023.fig.002d
(d)
Figure 2: Brain of control group (a and b). (a) The neuroepithelium (bold arrow) is of normal cellularity and architecture, with the supportive astroglial tissue (thin arrow) at ×100 (H and E). (b) The astro-glial tissue is of normal cellularity, showing pyramidal astro-glial cells, with indistinct cell boundaries, having fibrillary cytoplasmic processes (arrows) at ×400 (H and E). Brain of exposed group (c and d). (c) The field shows marked astro-glial hypercellularity (i.e., reactive gliosis) at ×200 (H and E). (d) The astro-glial tissue shows marked hypercellularity (i.e., secondary reactive gliosis), with a diffused vascular congestion (arrows) accompanied by extravasation of RBCs, as well as partial obliteration of lumen with thickened hypertrophied fibrous vessel wall (encircled) at ×300 (H and E).