- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 716023, 7 pages
Assessment of Genotoxic and Cytotoxic Hazards in Brain and Bone Marrow Cells of Newborn Rats Exposed to Extremely Low-Frequency Magnetic Field
Department of Biophysics, Faculty of Science, Cairo University, Giza 12013, Egypt
Received 23 May 2012; Accepted 10 August 2012
Academic Editor: Brynn Levy
Copyright © 2012 Monira M. Rageh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- N. Wertheimer and E. Leeper, “Original contributions. Electrical wiring configurations and childhood cancer,” American Journal of Epidemiology, vol. 109, no. 3, pp. 273–284, 1979.
- H. Berg, “Problems of weak electromagnetic field effects in cell biology,” Bioelectrochemistry and Bioenergetics, vol. 48, no. 2, pp. 355–360, 1999.
- H. Lai and N. P. Singh, “Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells,” Bioelectromagnetics, vol. 18, no. 2, pp. 156–165, 1997.
- H. Lai and N. P. Singh, “Melatonin and N-tert-butyl-α-phenylnitrone block 60 Hz magnetic field-induced DNA single and double strand breaks in rat brain cells,” Journal of Pineal Research, vol. 22, no. 3, pp. 152–162, 1997.
- B. M. Svedenstål, K. J. Johanson, and K. Hansson Mild, “DNA damage induced in brain cells of CBA mice exposed to magnetic fields,” In Vivo, vol. 13, no. 6, pp. 551–552, 1999.
- B. M. Svedenstål, K. J. Johanson, M. O. Mattsson, and L. E. Paulsson, “DNA damage, cell kinetics and ODC activities studied in CBA mice exposed to electromagnetic fields generated by transmission lines,” In Vivo, vol. 13, no. 6, pp. 507–513, 1999.
- H. Yaguchi, M. Yoshida, G. R. Ding, K. Shingu, and J. Miyakoshi, “Increased chromatid-type chromosomal aberrations in mouse m5S cells exposed to power-line frequency magnetic fields,” International Journal of Radiation Biology, vol. 76, no. 12, pp. 1677–1684, 2000.
- R. Pasquini, M. Villarini, G. Scassellati Sforzolini, C. Fatigoni, and M. Moretti, “Micronucleus induction in cells co-exposed in vitro to 50 Hz magnetic field and benzene, 1,4-benzenediol (hydroquinone) or 1,2,4-benzenetriol,” Toxicology in Vitro, vol. 17, no. 5-6, pp. 581–586, 2003.
- D. D. Ager and J. A. Radul, “Effect of 60 Hz magnetic fields on ultraviolet light-induced mutation and mitotic recombination in Saccharomyces cerevisiae,” Mutation Research, vol. 283, no. 4, pp. 279–286, 1992.
- A. Antonopoulos, B. Yang, A. Stamm, W. D. Heller, and G. Obe, “Cytological effects of 50 Hz electromagnetic fields on human lymphocytes in vitro,” Mutation Research, vol. 346, no. 3, pp. 151–157, 1995.
- S. Amara, H. Abdelmelek, C. Garrel et al., “Influence of static magnetic field on cadmium toxicity: Study of oxidative stress and DNA damage in rat tissues,” Journal of Trace Elements in Medicine and Biology, vol. 20, no. 4, pp. 263–269, 2006.
- J. Everse and N. Hsia, “The toxicities of native and modified hemoglobins,” Free Radical Biology and Medicine, vol. 22, no. 6, pp. 1075–1099, 1997.
- B. A. Freeman and J. D. Crapo, “Biology of disease. Free radicals and tissue injury,” Laboratory Investigation, vol. 47, no. 5, pp. 412–426, 1982.
- N. Hogg and B. Kalyanaraman, “Nitric oxide and lipid peroxidation,” Biochimica et Biophysica Acta, vol. 1411, no. 2-3, pp. 378–384, 1999.
- S. Di Loreto, S. Falone, V. Caracciolo et al., “Fifty hertz extremely low-frequency magnetic field exposure elicits redox and trophic response in rat-cortical neurons,” Journal of Cellular Physiology, vol. 219, no. 2, pp. 334–343, 2009.
- National Research Council, Guide for the Care and Use of Laboratory Animals, National Academy Press, Washington, DC, USA, 1996.
- M. Nishikimi, N. Appaji Rao, and K. Yagi, “The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen,” Biochemical and Biophysical Research Communications, vol. 46, no. 2, pp. 849–854, 1972.
- E. Beautler, O. Duron, and B. M. Kelly, “Improved method for the determination of blood glutathione.,” The Journal of Laboratory and Clinical Medicine, vol. 61, pp. 882–888, 1963.
- M. Uchiyama and M. Mihara, “Determination of malonaldehyde precursor in tissues by thiobarbituric acid test,” Analytical Biochemistry, vol. 86, no. 1, pp. 271–278, 1978.
- P. Moller, L. E. Knudsen, S. Loft, and H. Wallin, “The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors,” Cancer Epidemiology Biomarkers and Prevention, vol. 9, no. 10, pp. 1005–1015, 2000.
- W. M. Awara, S. H. El-Nabi, and M. El-Gohary, “Assessment of vinyl chloride-induced DNA damage in lymphocytes of plastic industry workers using a single-cell gel electrophoresis technique,” Toxicology, vol. 128, no. 1, pp. 9–16, 1998.
- N. P. Singh, M. T. McCoy, R. R. Tice, and E. L. Schneider, “A simple technique for quantitation of low levels of DNA damage in individual cells,” Experimental Cell Research, vol. 175, no. 1, pp. 184–191, 1988.
- R. Tice, E. Agurell, D. Anderson, et al., “Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing,” Environmental and Molecular Mutagenesis, vol. 35, no. 3, pp. 206–221, 2000.
- W. Schmidt, “The micronucleus test for cytogenetic analysis,” in Chemical Mutagens, Principles and Methods for Their Detection, A. Hollaender, Ed., pp. 31–53, Plenum Press, New York, NY, USA, 1976.
- D. K. Agarwal and L. K. S. Chauhan, “An improved chemical substitute for fetal calf serum for the micronucleus test,” Biotechnic and Histochemistry, vol. 68, no. 4, pp. 187–188, 1993.
- I. Adler, “Cytogenetic tests in mammals,” in Mutagenicity Testing, A Practical Approach, S. Venitt and J. M. Parry, Eds., pp. 275–306, IRL Press, Oxford, UK, 1984.
- B. Brocklehurst and K. A. McLauchlan, “Free radical mechanism for the effects of environmental electromagnetic fields on biological systems,” International Journal of Radiation Biology, vol. 69, no. 1, pp. 3–24, 1996.
- B. Zheng, G. Yao, L. Xie, Y. Lin, D. Q. H. Lu, and Chiang, “Effects of 50 Hz magnetic fields on lipid peroxydation and antioxidase activities in brain tissue of mice,” in Proceedings of the 2nd World Congress for Electricity and Magnetism in Biology and Medicine, 1997.
- T. B. Kryston, A. B. Georgiev, P. Pissis, and A. G. Georgakilas, “Role of oxidative stress and DNA damage in human carcinogenesis,” Mutation Research, vol. 711, no. 1-2, pp. 193–201, 2011.
- I. Udroiu, M. Cristaldi, L. A. Ieradi, A. Bedini, L. Giuliani, and C. Tanzarella, “Clastogenicity and aneuploidy in newborn and adult mice exposed to 50 Hz magnetic fields,” International Journal of Radiation Biology, vol. 82, no. 8, pp. 561–567, 2006.
- L. Dominici, M. Villarini, C. Fatigoni, S. Monarca, and M. Moretti, “Genotoxic hazard evaluation in welders occupationally exposed to extremely low-frequency magnetic fields ( ELF-MF),” International Journal of Hygiene and Environmental Health, vol. 215, no. 1, pp. 68–75, 2011.
- H. Lai and N. P. Singh, “Magnetic field-induced DNA strand breaks in brain cells of the rat,” Environmental Health Perspectives, vol. 112, no. 6, pp. 687–694, 2004.
- A. Lacy-Hulbert, J. C. Metcalfe, and R. Hesketh, “Biological responses to electromagnetic fields,” FASEB Journal, vol. 12, no. 6, pp. 395–420, 1998.