Table 1: Relative expression and nanoLC-ESI-LIT-MS/MS-based identification of differentially expressed proteins, as revealed by 2D-DIGE analysis of synaptosomal preparations.

SpotRatio 𝑃 valueAccessionProteinShort namepI/Mw theoretical (kDa)PeptidesSequence coverageMascot score

144−1.850.029P33175Kinesin heavy chain isoform 5AKif5a5.67/11722131

162−1.530.049P28738Kinesin heavy chain isoform 5CKif5c5.84/10968281

288−1.410.047P17710Hexokinase-1Hk16.44/1081012407

425−1.270.025Q62108Disks large homolog 4Dlg45.56/8034116

8901.510.043P50516 V-type proton ATPase catalytic subunit AAtp6v1a5.42/68511323
P63017 Heat shock cognate 71 kDa proteinHspa85.37/71712264
O08553Dihydropyrimidinase-related protein 2Dpysl25.95/6236163

891−1.380.045P50516V-type proton ATPase catalytic subunit AAtp6v1a5.42/68814430
P63017Heat shock cognate 71 kDa proteinHspa85.37/7159287
O08553Dihydropyrimidinase-related protein 2Dpysl25.95/6235123

9181.380.014P50516 V-type proton ATPase catalytic subunit AAtp6v1a5.42/68917433
O08553Dihydropyrimidinase-related protein 2Dpysl25.95/62512427
P63017Heat shock cognate 71 kDa proteinHspa85.37/71813336

9571.310.041O08553Dihydropyrimidinase-related protein 2Dpysl25.95/621331925
P97379Ras GTPase-activating protein-binding protein 2G3bp25.44/5436146

10431.350.026Q8BMF4Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialDlat5.70/5959260

2632−1.260.018P62874Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Gnb15.60/37621361
P62880Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2Gnb25.60/37621327

2872−1.290.041P63328Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformPpp3ca5.58/59410180

3391−1.500.043Q9D7X3Dual specificity protein phosphatase 3Dusp36.07/20324217