730462.fig.004a
(a)
730462.fig.004b
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730462.fig.004c
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730462.fig.004d
(d)
Figure 4: Effect of genistein on thoracic aortas morphological changes measured by immunohistochemical staining of vWF (×100). (a) Con; (b) Met; (c) OVX + Met; (d) OVX + Met + GST. The continuity of vWF positive staining (indicating endothelium) was interrupted in OVX + Met group, with negative staining in some parts of the inner wall (showed by ), while genistein could markedly improve the continuity of vWF positive staining of OVX + Met group.