Research Article

Desipramine Pretreatment Improves Sympathetic Remodeling and Ventricular Fibrillation Threshold after Myocardial Ischemia

Table 3

TH- and GAP43-positive nerve fiber density in the infarct border zone (um²/mm², mean ± SD).

GroupTHGAP43TH/GAP43 (%)

Sham-operated group 1 2 7 1 7 . 5 ± 4 7 0 3 . 0 1 8 5 3 8 . 7 ± 9 4 1 5 . 1 6 8 . 6 ± 9 . 8
Control ischemic group 1 2 6 7 1 7 . 5 ± 1 9 9 0 0 . 3 * 1 5 3 0 4 2 . 5 ± 2 0 3 8 6 . 8 * 8 2 . 8 ± 1 1 . 3 *
Preischemic treatment Group 4 6 7 0 2 . 5 ± 8 8 7 8 . 6 * 6 1 1 2 1 . 2 ± 4 2 2 3 . 5 *76.4 ± 12.1*
Delayed application group 8 2 4 7 2 . 5 ± 1 7 9 0 2 . 6 *# 1 0 2 0 4 2 . 5 ± 1 8 9 4 3 . 6 *# 8 0 . 8 ± 1 0 . 5 *

* 𝑃 < 0 . 0 5 when compared with the sham-operated group.
𝑃 < 0 . 0 5 when compared with the control ischemic group.
# 𝑃 < 0 . 0 5 when compared with the preischemic treatment group.