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BioMed Research International
/
2012
/
Article
/
Tab 11
/
Research Article
Optimal Control of Gene Mutation in DNA Replication
Table 11
12 kinds of mutagens, each corresponding to major transfer patterns, and the probabilities of different mutagens on different transfer patterns.
Index (
𝑙
1
)
From
To
Major transfer pattern
A
G
C
T
1
𝐴
𝑝
(
ℎ
)
1
,
𝐴
𝐴
𝑝
(
ℎ
)
1
,
𝐴
𝐺
𝑝
(
ℎ
)
1
,
𝐴
𝐶
𝑝
(
ℎ
)
1
,
𝐴
𝑇
𝐴
→
𝐴
2
𝐴
𝑝
(
ℎ
)
2
,
𝐴
𝐴
𝑝
(
ℎ
)
2
,
𝐴
𝐺
𝑝
(
ℎ
)
2
,
𝐴
𝐶
𝑝
(
ℎ
)
2
,
𝐴
𝑇
𝐴
→
𝐺
3
𝐴
𝑝
(
ℎ
)
3
,
𝐴
𝐴
𝑝
(
ℎ
)
3
,
𝐴
𝐺
𝑝
(
ℎ
)
3
,
𝐴
𝐶
𝑝
(
ℎ
)
3
,
𝐴
𝑇
𝐴
→
𝐶
4
𝐺
𝑝
(
ℎ
)
4
,
𝐺
𝐴
𝑝
(
ℎ
)
4
,
𝐺
𝐺
𝑝
(
ℎ
)
4
,
𝐺
𝐶
𝑝
(
ℎ
)
4
,
𝐺
𝑇
𝐺
→
𝐴
5
𝐺
𝑝
(
ℎ
)
5
,
𝐺
𝐴
𝑝
(
ℎ
)
5
,
𝐺
𝐺
𝑝
(
ℎ
)
5
,
𝐺
𝐶
𝑝
(
ℎ
)
5
,
𝐺
𝑇
𝐺
→
𝐺
6
𝐺
𝑝
(
ℎ
)
6
,
𝐺
𝐴
𝑝
(
ℎ
)
6
,
𝐺
𝐺
𝑝
(
ℎ
)
6
,
𝐺
𝐶
𝑝
(
ℎ
)
6
,
𝐺
𝑇
𝐺
→
𝑇
7
𝐶
𝑝
(
ℎ
)
7
,
𝐶
𝐴
𝑝
(
ℎ
)
7
,
𝐶
𝐺
𝑝
(
ℎ
)
7
,
𝐶
𝐶
𝑝
(
ℎ
)
7
,
𝐶
𝑇
𝐶
→
𝐴
8
𝐶
𝑝
(
ℎ
)
8
,
𝐶
𝐴
𝑝
(
ℎ
)
8
,
𝐶
𝐺
𝑝
(
ℎ
)
8
,
𝐶
𝐶
𝑝
(
ℎ
)
8
,
𝐶
𝑇
𝐶
→
𝐶
9
𝐶
𝑝
(
ℎ
)
9
,
𝐶
𝐴
𝑝
(
ℎ
)
9
,
𝐶
𝐺
𝑝
(
ℎ
)
9
,
𝐶
𝐶
𝑝
(
ℎ
)
9
,
𝐶
𝑇
𝐶
→
𝑇
10
𝑇
𝑝
(
ℎ
)
1
0
,
𝑇
𝐴
𝑝
(
ℎ
)
1
0
,
𝑇
𝐺
𝑝
(
ℎ
)
1
0
,
𝑇
𝐶
𝑝
(
ℎ
)
1
0
,
𝑇
𝑇
𝑇
→
𝐺
11
𝑇
𝑝
(
ℎ
)
1
1
,
𝑇
𝐴
𝑝
(
ℎ
)
1
1
,
𝑇
𝐺
𝑝
(
ℎ
)
1
1
,
𝑇
𝐶
𝑝
(
ℎ
)
1
1
,
𝑇
𝑇
𝑇
→
𝐶
12
𝑇
𝑝
(
ℎ
)
1
2
,
𝑇
𝐴
𝑝
(
ℎ
)
1
2
,
𝑇
𝐺
𝑝
(
ℎ
)
1
2
,
𝑇
𝐶
𝑝
(
ℎ
)
1
2
,
𝑇
𝑇
𝑇
→
𝑇