Urinary Neutrophil Gelatinase-Associated Lipocalin Is a Potential Biomarker for Renal Damage in Patients with Systemic Lupus Erythematosus

Figure 1

Comparison of 24-hour urinary excretion of neutrophil gelatinase-associated lipocalin (NGAL) (a), interleukin (IL)-10 (b), transforming growth factor (TGF)-β1 (c), and tumor necrosis factor (TNF)-α (d) in 5 groups: systemic lupus erythematosus (SLE)-active nephritis (𝑛=24), SLE-renal (24 SLE-active nephritis + 10 SLE-proteinuria only, 𝑛=34), SLE-non-renal (𝑛=8), disease control (DC, 𝑛=14), and normal control (NC, 𝑛=12) groups. ^† 𝑃<0.05 and ^†† 𝑃<0.01, are shown above panels, for comparison among the different patient groups. *𝑃<0.05, **𝑃<0.01, and NS, not significant, are shown below the 𝑥-axis of panels, in comparison with the NC group. The median value in each study group is shown by a horizontal line.

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