Aberrant Expression of N-Methylpurine-DNA Glycosylase Influences Patient Survival in Malignant Gliomas

Figure 2

Expression of MPG gene in glioma and nonneoplastic brain tissues by quantitative real-time PCR analysis. (a) MPG gene expression levels in glioma (lanes 2 and 4) and nonneoplastic brain tissues (lanes 1 and 3). (b) MPG gene expression levels in glioma with different WHO grades. Lanes 1 to 4: MPG gene expression in glioma tissues with WHO grade I, II, III, and IV, respectively. (c) MPG gene expression levels in nonneoplastic brain tissues and glioma with different WHO grades. “N” refers to nonneoplastic brain tissues; “Ca” refers to glioma tissues; “Ca_I”~“Ca_IV” refer to glioma tissues with WHO grade I~IV. β-actin was used as an internal control for quantitative real-time PCR analysis. Values are means ±SD. ^∗𝑃<0.05, comparison with nonneoplastic brain tissues; ^∗∗𝑃<0.001, comparison with nonneoplastic brain tissues.

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