Attenuating Effect of Ginkgo biloba Leaves Extract on Liver Fibrosis Induced by Thioacetamide in Mice
Table 1
Plasma ALT, AST, GGT, ALP, total protein, albumin, glucose, triglycerides, cholesterol, HDL-L, and LDL-C levels (mean ± SD) of control, TAA, TTA plus G. biloba leaves extract, and G. biloba leaves extract treated mice ( = 7). Percentage changes are included in parentheses.
Parameters
Treatments
Control
TAA
TAA + leaves extract
Leaves extract
ALT (U/L)
ab
33.63 ± 6.35ac
(+117.8)
(+26.9)
AST (U/L)
ab
49.87 ± 11.64
(+101.8)
(+20.5)
GGT (U/L)
ab
5.83 ± 1.33c
(+141.1)
(+21.7)
ALP (U/L)
ab
127.38 ± 17.78
(+54.0)
(+7.4)
Total protein (g/dL)
ab
5.36 ± 0.67
(−18.3)
Albumin (g/dL)
ab
3.30 ± 0.55
(−22.2)
Glucose (mg/dL)
ab
76.14 ± 6.87c
)
Triglycerides (mg/dL)
136.14 ± 16.38ab
99.14 ± 17.7ac
(+94.5)
(+41.6)
Cholesterol (mg/dL)
ab
139.29 ± 29.23ac
(+90.7)
(+50.7)
HDL-C (mg/dL)
ab
38.14 ± 2.0a
(−21.5)
LDL-C (mg/dL)
ab
33.57 ± 3.82ac
(+85.6)
(+35.0)
(−8.5)
aIndicates a significant difference between control and treated groups.
bIndicates a significant difference between the group treated with TAA and groups treated with TAA plus G. biloba leaves extract and G. biloba leaves extract.
cIndicates a significant difference between the group treated with TAA plus G. biloba leaves extract and group treated with G. biloba leaves extract.