Controlling Self-Renewal and Differentiation of Stem Cells via Mechanical Cues
Figure 2
The concept of force isotropy applied to cells: (a) anisotropic and (b) isotropic cytoskeletal tension caused by cell contraction either in the niche, or during cell migration through the extracellular matrix; (c) anisotropic and (d) isotropic extracellular forces; is cyclic matrix stress, is cyclic fluid-induced shear, and is cyclic pressurization.