Dickkopf-1 Expression Is a Novel Prognostic Marker for Gastric Cancer

Table 1

Correlations of Dickkopf-1 expression with the clinicopathological features of gastric cancer.

Features	No. of cases	Dickkopf-1 expression		𝑃
		High	Low
Age (years)	328	57.2±9.6	61.9±11.8	NS
Gender
Male	235	133	102	NS
Female	93	62	31
Tumor Location
Proximal	42	27	15	NS
Middle	123	70	53
Distal	163	97	66
Tumor size
<5 cm	192	116	76	NS
≥5 cm	136	79	57
Lauren classification
Intestinal	168	100	68	NS
Diffuse	160	95	65
Histology
Papillary adenocarcinoma	12	5	7	NS
Tubular adenocarcinoma	245	158	87
Mucinous adenocarcinoma	22	12	10
Signet-ring cell	49	20	29
Histologic differentiation
Well-moderately	96	61	35	NS
Poorly	220	132	88
Other	3	2	1
Invasion depth
T1	68	14	54	<0.01
T2	78	35	43
T3	130	101	29
T4	52	45	7
TNM stages
I	68	14	54	<0.01
II	78	35	43
III	130	101	29
IV	52	45	7
Vessel invasion
No	201	95	106	<0.01
Yes	127	100	27
Lymphatic metastasis
No	126	45	81	<0.01
Yes	202	150	52
Regional lymph nodes
PN0	125	37	88	<0.01
PN1	102	69	33
PN2	75	66	9
PN3	26	23	3
Distant metastasis
No	282	155	127	<0.01
Yes	46	40	6

“NS” refers to no significance.