Review Article

Modulation of Tight Junction Structure and Function by Kinases and Phosphatases Targeting Occludin

Table 1

Summary of known occludin phosphorylation sites in the context of the kinases or stimuli that induce phosphorylation at these sites and the effects on TJ function generated by induced or inhibited phosphorylation. Green label: kinase overexpression, stimulation or phospho-mimetic occludin variant; red label: kinase knockdown, inhibition or occludin variant that cannot be phosphorylated at the specified amino acid site.