Research Article
Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development
Table 1
Curated vaccine adjuvants used in at least five vaccines curated in VIOLIN.
| | Adjuvant type (number of adjuvants) | Adjuvants with >5 vaccines in VIOLIN | Number of vaccines |
| | Mineral salts (13) | | 154 | | Alhydrogel | 13 | | Aluminum hydroxide vaccine adjuvant | 62 | | Aluminum phosphate vaccine adjuvant | 50 | | Aluminum potassium sulfate adjuvant | 6 | | Aluminum vaccine adjuvant* | 14 | | Emulsions (15) | | 118 | | Freund’s complete adjuvant | 42 | | Freund’s incomplete adjuvant | 42 | | Montanide ISA 720 adjuvant | 6 | | Ribi vaccine adjuvant | 11 | | Microorganism-derived (18) | | 73 | | Cholera toxin | 17 | | Cholera toxin B subunit | 6 | | CpG DNA vaccine adjuvant | 12 | | LTR192G vaccine adjuvant | 6 | | MPL adjuvant | 10 | | Synthetic adjuvant (28) | | 28 | | Cytokines as adjuvants (9) | | 20 | | IL-12 vaccine adjuvant | 9 | | Tensoactive compounds (5) | | 12 | | Quil-A vaccine adjuvant | 5 | | Combination vaccine adjuvants (6) | | 9 | | Particulate antigen delivery systems (9) | | 11 | | Carbohydrates (2) | | 1 |
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Note: *shows those aluminum vaccine adjuvants that were used but without more specific details (e.g., using aluminum hydroxide).
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