Research Article
Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development
Table 4
Microorganism-derived adjuvants.
| Adjuvant name | Number of Vaccines | Mechanism | Route | Licensed |
| Cholera toxin | 17 | Immunostimulant | Mucosal | No | CpG DNA vaccine adjuvant | 12 | Immunostimulant | Either * | No | MPL adjuvant | 10 | Immunostimulant | Either | As part of AS04 | Cholera toxin B subunit | 6 | Immunostimulant | Mucosal | No | LTR192G vaccine adjuvant | 6 | Immunostimulant | Mucosal | No | Bordetella pertussis component vaccine adjuvant | 3 | Immunostimulant | Parenteral | Yes | E. coli heat-labile toxin, LT | 3 | Immunostimulant | Mucosal | No | CTA1-DD gene fusion protein | 2 | Immunostimulant | Either | No | Etx B subunit adjuvant | 2 | Immunostimulant | Either | No | Killed Corynebacterium parvum vaccine adjuvant | 2 | Immunostimulant | Parenteral | No | Lipopolysaccharide vaccine adjuvant | 2 | Immunostimulant | Either | No | LTK63 vaccine mutant adjuvant | 2 | Immunostimulant | Mucosal | No | Corynebacterium-derived P40 vaccine adjuvant | 1 | Immunostimulant | Parenteral | No | Flagellin vaccine adjuvant | 1 | Immunostimulant | Either | No | LTK72 vaccine adjuvant | 1 | Immunostimulant | Mucosal | No | MPL-SE vaccine adjuvant | 1 | Immunostimulant | Parenteral | No | Non-toxic mutant E112K of Cholera Toxin mCT-E112K | 1 | Immunostimulant | Mucosal | No | Ty particles vaccine adjuvant | 1 | Vehicle | Parenteral | No |
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Note: *either means either mucosal or parenteral route.
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