Vaxjo: A Web-Based Vaccine Adjuvant Database and Its Application for Analysis of Vaccine Adjuvants and Their Uses in Vaccine Development

Table 5

Vaccines with adjuvants by vaccine-targeted pathogens or diseases.

Pathogen or disease	Number of pathogen species	Subunit vaccines	Toxoid vaccines	DNA vaccines	Conjugate vaccines	Live vaccines	Killed vaccines	RCV vaccine**	VDP***	Total
Gram+ bacteria	11/14*	39	26	2	6	0	4	1	18	96
Gram− bacteria	22/48	96	6	2	7	0	2	5	13	130
Viruses	27/87	43	0	5	0	2	19	1	13	83
Fungi	1/1	3	0	0	0	0	0	0	0	3
Parasite	15/21	50	0	1	0	1	1	2	0	55
Cancer	—	11	0	1	0	1	0	0	0	13
Allergy	—	1	0	1	0	0	0	0	0	2
Total	80/173	245	32	14	13	4	26	9	44	384

*11/14 means 11 out of 14 spp. that have adjuvanted vaccines. Other numbers in this column use the same representation.
**RCV stands for recombinant vector vaccine.
*** VDP stands for vaccine made with different preparation methods, including (1) vaccine containing subunit component and inactivated whole organism, (2) vaccine containing DNA vaccine for priming and subunit vaccine for boosting, and (3) vaccine containing DNA vaccine for priming and Ad vector vaccine for boosting.