Research on Plants for the Understanding of Diseases of Nuclear and Mitochondrial Origin

Figure 2

Sequence alignment of NDUFS4 homologues from different organisms showing the high conservation in the flanking region of D119. The amino acid sequence of Homo sapiens (accession no. NP_002486.1), Mus musculus (accession no. NP_035017.2), Bos taurus (accession no. DAA17925.1), Drosophila melanogaster (accession no. NP_573385), Arabidopsis thaliana (accession no. Q9FJW4), Populus trichocarpa (accession no. XP_002310893), Hordeum vulgare (accession no. BAK01929), Zea mays (accession no. NP_001132398), Oryza sativa (accession no. NP_001060126) and Glycine max (accession no. NP_001235335) are shown. Alignment was performed by using the CLUSTALW2 method (Protein Weight Matrix Blosum, clustering NJ) (http://www.ebi.ac.uk/Tools/msa/clustalw2/). The conserved Asp residue is shown in grey.