About this Journal Submit a Manuscript Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 878107, 3 pages
Research Article

Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome

1Department of Dermatopathology, University Hospital Sart Tilman, 4000 Liège, Belgium
2Department of Rheumatology, Saint-Luc University Hospital, 1200 Brussels, Belgium

Received 13 March 2012; Accepted 12 July 2012

Academic Editor: Richard Tucker

Copyright © 2012 Trinh Hermanns-Lê et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Beighton, A. de Paepe, B. Steinmann, P. Tsipouras, and R. J. Wenstrup, “Ehlers-Danlos syndrome: revised nosology, Villefranche, 1997,” American Journal of Medical Genetics, vol. 77, no. 1, pp. 31–37.
  2. F. Henry, V. Goffin, C. Piérard-Franchimont, and G. E. Piérard, “Mechanical properties of skin in Ehlers-Danlos syndrome, types I, II, and III,” Pediatric Dermatology, vol. 13, no. 6, pp. 464–467, 1996. View at Scopus
  3. U. Seçkin, B. S. Tur, O. Yilmaz, I. Yaǧci, H. Bodur, and T. Arasil, “The prevalence of joint hypermobility among high school students,” Rheumatology International, vol. 25, no. 4, pp. 260–263, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. D. B. Everman and N. H. Robin, “Hypermobility syndrome,” Pediatrics in Review, vol. 19, no. 4, pp. 111–117, 1998. View at Scopus
  5. M. R. Simpson, “Benign joint hypermobility syndrome: evaluation, diagnosis, and management,” Journal of the American Osteopathic Association, vol. 106, no. 9, pp. 531–536, 2006. View at Scopus
  6. Z. S. Al-Rawi, A. J. Al-Aszawi, and T. Al-Chalabi, “Joint mobility among university students in Iraq,” British Journal of Rheumatology, vol. 24, no. 4, pp. 326–331, 1985. View at Scopus
  7. F. N. Birrell, A. O. Adebajo, B. L. Hazleman, and A. J. Silman, “High prevalence of joint laxity in West Africans,” British Journal of Rheumatology, vol. 33, no. 1, pp. 56–59, 1994. View at Scopus
  8. P. Narcisi, A. J. Richards, S. D. Ferguson, and F. M. Pope, “A family with Ehlers-Danlos syndrome type III/articular hypermobility syndrome has a glycine 637 to serine substitution in type III collagen,” Human Molecular Genetics, vol. 3, no. 9, pp. 1617–1620, 1994. View at Scopus
  9. M. C. Zweers, W. B. Dean, T. H. van Kuppevelt, J. Bristow, and J. Schalkwijk, “Elastic fiber abnormalities in hypermobility type Ehlers-Danlos syndrome patients with tenascin-X mutations,” Clinical Genetics, vol. 67, no. 4, pp. 330–334, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. I. Hausser and I. Anton-Lamprecht, “Differential ultrastructural aberrations of collagen fibrils in Ehlers-Danlos syndrome types I–IV as a means of diagnostics and classification,” Human Genetics, vol. 93, no. 4, pp. 394–407, 1994. View at Scopus
  11. T. Kobayasi, “Abnormality of dermal collagen fibrils in Ehlers Danlos syndrome. Anticipation of the abnormality for the inherited hypermobile disorders,” European Journal of Dermatology, vol. 14, no. 4, pp. 221–229, 2004. View at Scopus
  12. T. Hermanns-Lê and G. E. Piérard, “Ultrastructural alterations of elastic fibers and other dermal components in Ehlers-Danlos syndrome of the hypermobile type,” American Journal of Dermatopathology, vol. 29, no. 4, pp. 370–373, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Grahame, H. A. Bird, and A. Child, “The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS),” Journal of Rheumatology, vol. 27, no. 7, pp. 1777–1779, 2000. View at Scopus
  14. R. Grahame, “Joint hypermobility and genetic collagen disorders: are they related?” Archives of Disease in Childhood, vol. 80, no. 2, pp. 188–191, 1999. View at Scopus
  15. R. Grahame, “Heritable disorders of connective tissue,” Bailliere's Best Practice and Research in Clinical Rheumatology, vol. 14, no. 2, pp. 345–361, 2000. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Adib, K. Davies, R. Grahame, P. Woo, and K. J. Murray, “Joint hypermobility syndrome in childhood. A not so benign multisystem disorder?” Rheumatology, vol. 44, no. 6, pp. 744–750, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. M. C. Zweers, M. Kucharekova, and J. Schalkwijk, “Tenascin-X: a candidate gene for benign joint hypermobility syndrome and hypermobility type Ehlers-Danlos syndrome?” Annals of the Rheumatic Diseases, vol. 64, no. 3, pp. 504–505, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Hermanns-Lê and G. E. Piérard, “Collagen fibril arabesques in connective tissue disorders,” American Journal of Clinical Dermatology, vol. 7, no. 5, pp. 323–326, 2006. View at Publisher · View at Google Scholar · View at Scopus