Table 1: Mixed acid-base disturbances in COPD.

Acute on chronic respiratory acidosisRespiratory acidosis and metabolic alkalosis

Reexacerbation of COPDVolume depletion
Diuretics
Vomiting
Severe hypokalemia
Steroids
Posthypercapnic alkalosis

Respiratory acidosis and metabolic acidosisResp. acidosis, met. acidosis, and met. alkalosis

Severe hypoxemia
Acute pulmonary edemaRenal failure and vomiting
Severe hypoxemia and volume depletion
Sepsis and hypokalemia
Renal failure
Sepsis
Shock
Diabetes mellitus
Acute alcoholism
Exogenous poisoning