Curcumin Attenuates Gastric Cancer Induced by N-Methyl-N-Nitrosourea and Saturated Sodium Chloride in Rats

Table 2

The results of phospho-IκBα-relative expression, 8-OHdG-immunoreactive cells (%), and cyclin D1-immunoreactive cells (%).

Parameters/Group	CO (𝑁=6)	CC (𝑁=6)	MNU + s-NaCl (𝑁=6)	MNU + s-NaCl + C3W (𝑁=5)		MNU + s-NaCl + C20W (𝑁=6)
				C3W benign (𝑁=2)	C3W cancer (𝑁=3)	C20W benign (𝑁=3)	C20W cancer (𝑁=3)
Phospho-IκBα	0.51±0.11^†	0.54±0.18^†	0.82±0.18 *	0.46±0.04^†	0.60±0.29	0.51±0.08^†	1.16±0.34^**,†
8-OHdG	44.42±3.41^††	40.39±3.53^††	53.06±5.96 **	49.28±7.43	48.06±3.47	44.99±3.51^†	47.77±2.55
Cyclin D1	38.58±5.37^††	42.53±6.90^††	54.91±7.93 **	4.33±1.27 *	54.92±3.87 **	45.31±6.29	53.82±11.01 **

These data were presented as the mean ± SD. *Represented significant difference compared with CO group (𝑃<0.05 ). **Represented significant difference compared with CO group (𝑃<0.01 ). ^†Represented significant difference compared with MNU + s-NaCl group (𝑃<0.05). ^††Represented significant difference compared with MNU + s-NaCl group (𝑃<0.01).