An In Vivo Rabbit Model for the Evaluation of Antimicrobial Peripherally Inserted Central Catheter to Reduce Microbial Migration and Colonization as Compared to an Uncoated PICC
Figure 3
Representative digital micrographs taken during catheter explant and necropsy on rabbit 10. (a) Test article side: note that the fibrous capsule is minimal, and there is no evidence of pus or irritation. (b) Control article side: the digital image demonstrates indicators of infection uniformly across the three control replicates. Extensive pus, hyperemia, and fibrosis can be seen associated with the tissue around the control catheters.