Table 4: Tissue (CFU/g) Log reduction summary tables for day 30. Log reduction values higher than 4 are bold and underlined.
(a) For pairwise comparison, the mean Log10 CFU/g recovered from the three replicates of test articles/rabbit was subtracted from the mean Log10 CFU/g recovered from the three replicates of control articles/rabbit per segment

Sample location
Sample no.346810
DayRabbit no.Log 𝑅 (pairwise comparison)

3020.980.000.000.00−0.74
𝑃 0.370.000.000.000.76
303−1.052.431.162.484.52
𝑃 0.370.130.370.120.00
305−2.572.182.411.061.04
𝑃 0.120.120.120.370.37
306**3.910.000.000.000.00
𝑃 N/AN/AN/AN/AN/A
3084.902.243.703.685.18
𝑃 0.010.370.140.130.00

(b) For test article log reduction, the mean Log10 CFU/g recovered from the three replicates of test articles/rabbit was subtracted from the mean Log10 CFU from the initial inoculum counts that were exposed to the catheters at implantation

Sample location
Sample no.346810
DayRabbit no.Test article Log 𝑅 (based on initial inoculum)

3026.866.866.866.865.02
𝑃 0.370.000.000.000.76
3035.816.866.866.866.86
𝑃 0.370.130.370.120.00
3054.286.866.866.866.86
𝑃 0.120.120.120.370.37
306**6.866.866.866.866.86
𝑃 N/AN/AN/AN/AN/A
3086.866.866.866.866.86
𝑃 0.010.370.140.130.00

(c) For control article log reduction, the mean Log10 CFU/g recovered from the three replicates of control articles/rabbit was subtracted from the mean Log10 CFU from the initial inoculum counts that were exposed to the catheters at implantation

Sample location
Sample no.346810
DayRabbit no.Control article Log 𝑅 (based on initial inoculum)

3025.876.866.866.865.76
𝑃 0.370.000.000.000.76
3036.864.425.704.372.34
𝑃 0.370.130.370.120.00
3056.864.674.445.805.81
𝑃 0.120.120.120.370.37
306**2.956.866.866.866.86
𝑃 N/AN/AN/AN/AN/A
3081.954.623.153.181.67
𝑃 0.010.370.140.130.00

**indicates that control tunnels 1 and 3 on rabbit 6 were not available for analysis.