Table 2: Inhibitory effects of the compounds isolated from the P. vulgaris L. on rat lens aldose reductase (rAR) and human recombinant aldose reductase (rhAR).

CompoundsrARrhAR
I C 5 0 ( 𝜇 M)a

Quercetinb5.66 ± 1.0519.23 ± 0.74
1
2
38.35 ± 0.51
42.77 ± 0.4818.62 ± 0.40
53.20 ± 0.5512.58 ± 0.32
6

aInhibition rates were calculated as percentages with respect to the control value. The I C 5 0 values of each sample were estimated from the least-squares regression line of the logarithmic concentration plotted against inhibitory activity. bQuercetin was used as positive control. Inhibitory effect was expressed as mean ± SD of triplicate experiments.