The Inhibitory Effect of Prunella vulgaris L. on Aldose Reductase and Protein Glycation

Table 4

Inhibitory effects of the P. vulgaris L. on advanced glycation end products (AGEs).

Fraction	Concentration (𝜇g/mL)	Inhibition (%)	IC50 (𝜇g/mL)
	196.08	66.85 ± 0.13
Aminoguanidine^a	98.04	37.39 ± 0.52	143.92 ± 0.62
	19.61	3.96 ± 0.06
Water extract	196.08	29.26 ± 0.94	—
n-Hexane fr.	196.08	33.94 ± 0.41	—
	196.08	54.03 ± 1.00
Methylene chloride fr.	98.04	21.52 ± 0.64	186.72 ± 2.05
	19.61	3.66 ± 0.23
	196.08	68.31 ± 1.06
Ethyl acetate fr.	98.04	37.36 ± 0.89	141.34 ± 1.27
	19.61	4.92 ± 0.29
n-Butanol fr.	196.08	40.47 ± 0.68	—
Water fr.	196.08	30.24 ± 1.01	—

Inhibition rates were calculated as percentages with respect to the control value. ^aAminoguanidine was used as positive control. Inhibitory effect was expressed as mean ± SD of triplicate experiments.