The Inhibitory Effect of Prunella vulgaris L. on Aldose Reductase and Protein Glycation

Table 7

Antioxidant effects of the compounds isolated from the P. vulgaris L. on inhibition of the ABTS^•+.

Compounds	Concentration (𝜇g/mL)	Inhibition (%)	IC50 (𝜇M)
	16.67	99.44 ± 0.20
Trolox^a	3.33	45.48 ± 1.20	15.34 ± 0.40
	1.67	21.76 ± 1.15
	3.33	75.14 ± 1.08
1	1.67	34.65 ± 1.03	12.03 ± 0.24
	0.33	11.33 ± 0.31
	3.33	93.42 ± 0.58
2	1.67	53.79 ± 0.92	11.59 ± 0.22
	0.33	14.90 ± 0.34
	8.33	74.05 ± 0.69
3	3.33	59.65 ± 1.39	5.94 ± 1.01
	1.67	47.60 ± 1.35
	3.33	78.40 ± 1.17
4	1.67	36.50 ± 0.78	8.79 ± 0.10
	0.33	9.93 ± 0.27
	3.33	84.68 ± 1.41
5	1.67	50.17 ± 1.75	10.52 ± 0.28
	0.33	13.00 ± 0.13
	3.33	92.80 ± 1.50
6	1.67	52.73 ± 0.93	12.39 ± 0.33
	0.33	13.73 ± 0.37

Inhibition rate was calculated as percentage with respect to the control value. The IC₅₀ values of each sample were estimated from the least-squares regression line of the logarithmic concentration plotted against inhibitory activity. ^aTrolox was used as positive control. Inhibitory effect was expressed as mean ± SD of triplicate experiments.