Mannose-Binding Lectin Binds to Amyloid 𝜷 Protein and Modulates Inflammation

Figure 6

Effects of heparin on cytokine responses to Aβ40, Aβ42, IAV, or SA. The assays were performed as in Figure 5. Heparin was used at 0, 0.1, 1, and 10 μg/mL mixed with Aβ40, Aβ42, IAV, or SA. IL-6 and TNF-α in the culture supernatant were determined and are expressed as pg/mL ± SEM. Compared to WT serum, *𝑃<0.05; **𝑃<0.005; ***𝑃<0.0001 against all others.