Research Article

Inhibitory Effects of the Attenuated Salmonella typhimurium Containing the IL-2 Gene on Hepatic Tumors in Mice

Table 1

Subset of T lymphocytes in the peripheral blood (mean ± SD, %).

GroupsCD4+CD8+CD4+/CD8+

Normal 30.90 ± 3.7620.82 ± 5.501.58 ± 0.51
TP 35.08 ± 3.02**23.67 ± 3.83**1.48 ± 0.51
TPG33.90 ± 2.22**23.42 ± 2.64**1.45 ± 0.27
TPI 46.04 ± 3.52*30.30 ± 3.52*1.52 ± 0.42

* , TPI versus TP, TPG, Normal groups; ** , TP versus Normal group, TPG versus Normal group.
TP: attenuated S. typhimurium with the eukaryotic expression vector; TPI: attenuated S. typhimurium with the eukaryotic expression plasmid carrying IL-2 gene; TPG: attenuated S. typhimurium with the eukaryotic expression plasmid carrying GFP gene.