Research Article

Inhibitory Effects of the Attenuated Salmonella typhimurium Containing the IL-2 Gene on Hepatic Tumors in Mice

Table 3

Proliferation effect of splenic lymphocyte (mean ± SD).

GroupsTPTPILPSPHA

Normal 1.141 ± 0.0211.170 ± 0.0251.100 ± 0.0631.074 ± 0.036
TP1.266 ± 0.039*1.254 ± 0.095*1.273 ± 0.046*1.282 ± 0.051*
TPI1.374 ± 0.035*#1.402 ± 0.033*#1.353 ± 0.053*#1.383 ± 0.025*#

* , TPI versus Normal group, TP versus Normal group; # , TPI versus TP group.
TP: attenuated S. typhimurium with the eukaryotic expression vector; TPI: attenuated S. typhimurium with the eukaryotic expression plasmid carrying IL-2 gene.