Inhibitory Effects of the Attenuated Salmonella typhimurium Containing the IL-2 Gene on Hepatic Tumors in Mice

Table 4

Expression level of IL-2 protein in tissues of mice (mean ± SD).

Groups	Serum (ng/mL)	Liver (ng/g)	Spleen (ng/g)	Kidney (ng/g)	Lung (ng/g)	Intestine (ng/g)	Tumor (ng/g)
TPI	19.17 ± 10.6*	17.89 ± 1.0*	57.22 ± 6.19*	15.17 ± 1.41*	16.31 ± 1.46*	15.32 ± 1.56*	36.72 ± 7.55*
TP	8.48 ± 0.34*	8.78 ± 0.36**	10.34 ± 0.64*	7.89 ± 0.45**	7.50 ± 0.44**	7.38 ± 0.43**	9.30 ± 0.51**
Normal	2.06 ± 0.10	2.56 ± 0.12	3.12 ± 0.21	1.97 ± 0.10	1.69 ± 0.10	2.08 ± 0.11	3.37 ± 0.13

* 𝑃<0.01, TPI versus TP and Normal group; **𝑃<0.01, TP versus Normal group.
TP: attenuated S. typhimurium with the eukaryotic expression vector; TPI: attenuated S. typhimurium with the eukaryotic expression plasmid carrying IL-2 gene.