Review Article

Effects of Ginsenoside 𝐑 𝐛 𝟏 on Skin Changes

Figure 2

Effects of ginsenoside Rb1 on wound healing in mice [26]. After the burn wound was made by applying a customized soldering iron to the skin on the backs of male Balb/c mice (6 weeks old) for 10 s at 250°C, a sterile biopsy punch (8 mm diameter) was used to excise the burnt skin, leaving the underlying fasciae intact. All surgical treatments were performed under anesthesia with pentobarbital. Indicated amounts of ginsenoside Rb1 were applied to the burn wounds surface and then covered with a film dressing for 19 consecutive days. The burn wound site was photographed every other day and burn wound area was measured using a Coordinate Area and Curvimeter Machine (X-PLAN 360 dII). Values are the mean ± SE for 6–12 mice. *Significantly different from vehicle-treated mice, 𝑃 < 0 . 0 5 .
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