Research Article

Cytotoxicity of Bacterial Metabolic Products, including Listeriolysin O, on Leukocyte Targets

Table 1

List of bacterial strains.

Strain Characteristics References

L. monocytogenes 10403SWild type[17]
L. monocytogenes 1189
10403S strain harbouring point mutation in hly gene resulting in Cys484Ala substitution in LLO protein.[18]
L. monocytogenes 1190
10403S strain harbouring point mutation in hly gene resulting in Cys484Ser substitution in LLO protein. [18]
L. monocytogenes 1044
Nonhemolytic derivative of 10403S. Insertional mutant in hlyA gene. [19]
L. monocytogenes MACMackaness strain, hypervirulent isolate harbouring natural 𝑝 𝑟 𝑓 𝐴 mutation, overproducing determinants of pathogenesis. [20]
B. subtilis MB4Asporogenic derivative of strain ZB307 containing a
spoIIE::Tn9I7fQHU181::1ac55 insertion
[21, 22]
B. subtilis BR1-SMB4/pAG58/hly [16]
B. subtilis BR1-89MB4/pAG58/ 𝑙 𝑦 𝐶 4 8 4 𝐴 This work
B. subtilis BR1-90MB4/pAG58/ 𝑙 𝑦 𝐶 4 8 4 𝑆 This work