Research Article
Role of TGF-β1/Smad3 Signaling Pathway in Secretion of Type I and III Collagen by Vascular Smooth Muscle Cells of Rats Undergoing Balloon Injury
Table 2
Vascular lumen area and intima area in different groups.
| | Lumen area (mm2) | Intima area (mm2) | | 1 w | 2 w | 3 m | 1 w | 2 w | 3 m |
| Blank control | 0.39 ± 0.05 | 0.31 ± 0.03 | 0.14 ± 0.05 | 0.07 ± 0.01 | 0.12 ± 0.04 | 0.39 ± 0.03 | Negative control | 0.40 ± 0.07 | 0.33 ± 0.03 | 0.17 ± 0.02 | 0.08 ± 0.02 | 0.13 ± 0.02 | 0.42 ± 0.01 | Antisense Smad3 | 0.40 ± 0.08 | 0.40 ± 0.06▲ | 0.21 ± 0.03▲ | 0.06 ± 0.02 | 0.07 ± 0.01▲ | 0.17 ± 0.04▪ |
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Note: ▲ and ▪ versus negative control.
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