Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
Figure 1
Sensitivity of four human glioma cell lines to TMZ and VPA. (a) The number of viable cells was counted at 72 h after the addition of VPA (0–16 mM) to the culture medium. (b) The viability of glioma cells was also analyzed via MTT assay 72 h after TMZ (0–1,000 μM) treatment. Points, mean; bars, SE. The results are representative of three independent experiments.
