FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-<i>β</i>-CyD

<table>The gene delivery efficiencies of PEI600, PEI-<i>β</i>-CyD, CY11-PEI-<i>β</i>-CyD, and PEI25KDa with different N/P ratios in (a) COS-7, (b) HepG2, and (c) PC-3 cells. PEI25KDa at an N/P ratio of 10 shows the highest gene delivery efficiency. Data were shown as mean ± SD, (*<svg height="11.25" id="M6" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 56.150002 11.25" width="56.150002" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
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</svg> as compared with other samples in the same group). The green fluorescence emitted by green proteins expressed after the transfer of CY11-PEI-<i>β</i>-CyD/pEGFP at an N/P ratio of 25 to cells: (d) COS-7, (e) HepG2, and (f) PC-3 cells. A fluorescence microscope is used. Fluorescence is more evident in COS-7 (FGFR-positive) and HepG2 (FGFR-positive) cells than in PC-3 (FGFR-negative) ones.</table>

BioMed Research International

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Figure 5

Figure 5: FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-<i>β</i>-CyD 

BioMed Research International

FGF Receptor-Mediated Gene Delivery Using Ligands Coupled to PEI-β-CyD

Figure 5