Antiadherent and Antibiofilm Activity of Humulus lupulus L. Derived Products: New Pharmacological Properties

Table 2

Synergistic activity of subinhibitory concentrations of Humulus lupulus constituents and antibiotics belonging to various therapeutic classes, determined by the E-test strip/agar dilution method against S. aureus ATCC 29213.

Treatment	MIC [µg/mL]
	Oxacillin	Vancomycin	Linezolid
(Control)	0.125	1.0	0.5
Hop cones extract
1/2 MIC (15.6 µg/mL)	0.094	1.0	0.38
1/4 MIC (7.8 µg/mL)	0.094	1.0	0.5
Spent hops extract
1/2 MIC (1000 µg/mL)	0.094	1.0	0.5
1/4 MIC (500 µg/mL)	0.125	1.0	n.t.
Xanthohumol
1/2 MIC (7.8 µg/mL)	0.064	1.0	0.38
1/4 MIC (3.9 µg/mL)	0.094	1.0	0.5

n.t.: not tested.