Research Article
1,25-Dihydroxyvitamin D3 Inhibits the RANKL Pathway and Impacts on the Production of Pathway-Associated Cytokines in Early Rheumatoid Arthritis
Table 1
The serum levels of RANKL, OPG, and associated cytokines in RA patients versus control group.
| | RANKL (pmol/L) | OPG (pmol/L) | RANKL/OPG | TNF- (pg/mL) | IL-17 (pg/mL) | IL-6 (pg/mL) | IL-4 (pg/mL) |
| RA group | 100.17 ± 22.27 | 0.64 ± 0.17 | 169.57 ± 59.38 | 5.91 ± 2.53 | 42.56 ± 6.43 | 16.63 ± 12.00 | 2.72 ± 0.36 | Healthy control group | 75.82 ± 9.108 | 0.53 ± 0.16 | 149.00 ± 26.71 | 2.63 ± 0.27 | 21.10 ± 3.22 | 4.16 ± 2.27 | 2.72 ± 0.33 |
|
|
Values are expressed as mean ± standard deviation.
|