Table 4: The impact of 1,25(OH)2D3 at various concentrations on inflammation-related cytokines in the RA and healthy control group.

RANKL 
(pmol/L)
OPG 
(pmol/L)
RANKL/OPGTNF-
(pg/mL)
IL-17 
(pg/mL)
IL-6 
(pg/mL)
IL-4 
(pg/mL)

RA patient
 Anti-CD3/CD28100.72 ± 11.980.57 ± 0.15190.24 ± 51.25508.52 ± 90.94606.76 ± 49.797939.02 ± 2108.859.46 ± 4.15
 D180.23 ± 9.370.53 ± 0.15163.92 ± 56.07424.08 ± 81.69533.35 ± 47.475513.03 ± 3429.0811.56 ± 9.14
 D279.01 ± 15.410.48 ± 0.14167.83 ± 29.43381.56 ± 78.79425.75 ± 55.334554.65 ± 3156.5014.83 ± 13.65
 D393.75 ± 21.880.58 ± 0.13164.90 ± 35.68326.18 ± 87.34318.91 ± 85.913747.55 ± 1918.949.13 ± 5.88
Healthy control
 Anti-CD3/CD2883.09 ± 12.170.61 ± 0.07136.23 ± 13.42195.95 ± 52.83249.87 ± 17.632607.90 ± 232.986.77 ± 4.43
 D182.43 ± 10.190.66 ± 0.12129.67 ± 30.01168.60 ± 50.01219.48 ± 35.873229.37 ± 2029.547.27 ± 1.56
 D215.46 ± 8.950.45 ± 0.11175.07 ± 39.69174.97 ± 26.36211.48 ± 41.782601.70 ± 1032.239.47 ± 6.57
 D374.67 ± 12.610.55 ± 0.09139.44 ± 30.40128.73 ± 19.29206.53 ± 27.703236.45 ± 862.957.62 ± 3.31

Values are expressed as mean ± standard deviation.