Ethanol Extract of Cordyceps militaris Grown on Germinated Soybeans Attenuates Dextran-Sodium-Sulfate- (DSS-) Induced Colitis by Suppressing the Expression of Matrix Metalloproteinases and Inflammatory Mediators

Figure 1

Cordyceps militaris grown on germinated soybeans (GSC) extract attenuated the severity of DSS-induced acute colitis. (a) Survival curves of mice administered with the vehicle, DSS, and DSS + GSC extracts. (b) Change of body weight was measured. Statistical significance was assessed compared with control mice (^#𝑃<0.01 versus control; ^∗𝑃<0.01 versus DSS). (c) Disease activity index (DAI) score was monitored daily (𝑛≥15 per group). Data are expressed as mean ± standard deviation (SD) (𝑛≥15 per group). (d) Colon length of each mouse was measured. (^##𝑃<0.001 versus control; ^∗𝑃<0.01 versus DSS). DSS: dextran sulfate sodium; CM: Cordyceps militaris; GS: germinated soybeans; GSC: Cordyceps militaris grown on germinated soybeans.

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