Table 1: Histological score of DSS-induced colitis in GSC-treated mice.

Control3% DSS3% DSS + GSC

Loss of epithelium0.67 ± 0.582.67 ± 0.58a0.67 ± 1.15d
Loss of crypt0.33 ± 0.582.67 ± 0.58b1.33 ± 1.53c
Loss of goblet cells0.00 ± 0.002.33 ± 0.58b0.67 ± 1.15d
Infiltration of inflammatory cells0.00 ± 0.003.00 ± 0.00b1.33 ± 0.58d

Total1.00 ± 1.1610.67 ± 1.73b4.00 ± 4.41e

Each value represents the mean ± S.E.M. of ≥ 15 animals.
a < 0.01, b < 0.001 versus Control; c < 0.05, d < 0.01, and e < 0.001 versus DSS.
DSS: dextran sulfate sodium; GSC: Cordyceps  militaris grown on germinated soybeans.
3% DSS and GSC extract (500 mg/kg).