Chemical Modifications of PhTX-I Myotoxin from Porthidium hyoprora Snake Venom: Effects on Structural, Enzymatic, and Pharmacological Properties
Figure 8
In vitro cytotoxic activity of native PhTX-I PLA2 and their chemically modified derivatives with BPB, AA, NBSF, and NPSC on NCIH-3T3 (a) and NG97 (b) cell culture. Cell lysis was estimated by neutral red uptake assay. The cell death was determined in comparison of absorbance obtained from nontreated cells. Experiments were carried out in triplicate. *().
