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BioMed Research International
Volume 2013 (2013), Article ID 108902, 7 pages
http://dx.doi.org/10.1155/2013/108902
Research Article

The Glycosylation of AGP and Its Associations with the Binding to Methadone

1School of Life, Sport and Social Sciences, Edinburgh Napier University, Sighthill Campus, Edinburgh EH11 4BN, UK
2School of Nursing, Midwifery and Social Care, Edinburgh Napier University, Edinburgh EH11 4BN, UK
3Community Drug Problem Service, Spittal Street Centre, Edinburgh EH3 9DU, UK

Received 3 April 2013; Revised 21 June 2013; Accepted 21 June 2013

Academic Editor: Viness Pillay

Copyright © 2013 Jennifer L. Behan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. UNODC, World Drug Report 2010, Sales No.E.10.XI.13, United Nations Publication, 2010.
  2. N. McKeganey, M. Bloor, M. Robertson, J. Neale, and J. MacDougall, “Abstinence and drug abuse treatment: results from the drug outcome research in Scotland Study,” Drugs, vol. 13, no. 6, pp. 537–550, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. M. K. Romach, K. M. Piafsky, and J. G. Abel, “Methadone binding to orosomucoid (α1-acid glycoprotein): determinant of free fraction in plasma,” Clinical Pharmacology and Therapeutics, vol. 29, no. 2, pp. 211–217, 1981. View at Scopus
  4. O. Drummer and M. Odell, The Forensic Pharmacology Drugs of Abuse, Edited by O. H. Drummer, Hodder Arnold, 2001.
  5. M. M. Scimeca, S. R. Savage, R. Portenoy, and J. Lowinson, “Treatment of pain in methadone-maintained patients,” Mount Sinai Journal of Medicine, vol. 67, no. 5-6, pp. 412–422, 2000. View at Scopus
  6. F. Ceciliani and V. Pocacqua, “The acute phase protein α1-acid glycoprotein: a model for altered glycosylation during diseases,” Current Protein and Peptide Science, vol. 8, no. 1, pp. 91–108, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Kuroda, S. Matsumoto, A. Shibukawa, and T. Nakagawa, “Capillary electrophoretic study on pH dependence of enantioselective disopyramide binding to genetic variants of human α1-acid glycoprotein,” Analyst, vol. 128, no. 8, pp. 1023–1027, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. J. M. H. Kremer, J. Wilting, and L. H. M. Janssen, “Drug binding to human alpha-1-acid glycoprotein in health and disease,” Pharmacological Reviews, vol. 40, no. 1, pp. 1–47, 1988. View at Scopus
  9. A. Rostami-Hodjegan, K. Wolff, A. W. M. Hay, D. Raistrick, R. Calvert, and G. T. Tucker, “Population pharmacokinetics of methadone in opiate users: characterization of time-dependent changes,” British Journal of Clinical Pharmacology, vol. 48, no. 1, pp. 43–52, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Varki, R. D. Cummings, J. D. Esko, et al., Essentials of Glycobiology, Cold Spring Harbour Laboratory Press, 2nd edition, 2009.
  11. M. E. Taylor and K. Drickamer, Introduction to Glycobiology, Oxford University Press Limited, 2003.
  12. W. van Dijk, G. A. Turner, and A. Mackiewicz, “Changes in glycosylation of acute-phase proteins in health and disease: occurrence, regulation and function,” Glycosylation and Disease, vol. 1, no. 1, pp. 5–14, 1994. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Higai, Y. Aoki, Y. Azuma, and K. Matsumoto, “Glycosylation of site-specific glycans of α1-acid glycoprotein and alterations in acute and chronic inflammation,” Biochimica et Biophysica Acta, vol. 1725, no. 1, pp. 128–135, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. Z. H. Israili and P. G. Dayton, “Human alpha-1-glycoprotein and its interactions with drugs,” Drug Metabolism Reviews, vol. 33, no. 2, pp. 161–235, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. W. E. Muller, “Stereoselective plasma protein binding of drugs,” in Drug Stereochemistry: Analytical Methods and Pharmacology, I. W. Wainer and D. E. Drayer, Eds., p. 277, Marcel Dekker, New York, NY, USA, 1988.
  16. M. A. Elliott, H. G. Elliott, K. Gallagher, J. McGuire, M. Field, and K. D. Smith, “Investigation into the concanavalin A reactivity, fucosylation and oligosaccharide microheterogeneity of α1-acid glycoprotein expressed in the sera of patients with rheumatoid arthritis,” Journal of Chromatography B, vol. 688, no. 2, pp. 229–237, 1997. View at Publisher · View at Google Scholar · View at Scopus
  17. J.-Q. Fan, Y. Namiki, K. Matsuoka, and Y. C. Lee, “Comparison of acid hydrolytic conditions for Asn-linked oligosaccharides,” Analytical Biochemistry, vol. 219, no. 2, pp. 375–378, 1994. View at Publisher · View at Google Scholar · View at Scopus
  18. G. A. Turner, A. W. Skillen, and P. Buamah, “Relation between raised concentrations of fucose, sialic acid, and acute phase proteins in serum from patients with cancer: choosing suitable serum glycoprotein markers,” Journal of Clinical Pathology, vol. 38, no. 5, pp. 588–592, 1985. View at Scopus
  19. J. J. Listinsky, G. P. Siegal, and C. M. Listinsky, “Alpha-L-fucose: a potentially critical molecule in pathologic processes including neoplasia,” American Journal of Clinical Pathology, vol. 110, no. 4, pp. 425–440, 1998. View at Scopus
  20. S. S. Gustafsson, L. Vrang, Y. Terelius, and U. H. Danielson, “Quantification of interactions between drug leads and serum proteins by use of ‘binding efficiency’,” Analytical Biochemistry, vol. 409, no. 2, pp. 163–175, 2011. View at Publisher · View at Google Scholar · View at Scopus